dyclonine-7261 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the dyclonine-7261 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP13 A kinase (PRKA) anchor protein 13
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APC adenomatous polyposis coli
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD2B ATPase family, AAA domain containing 2B
ATP9A ATPase, class II, type 9A
ATXN3 ataxin 3
BATF3 basic leucine zipper transcription factor, ATF-like 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTN3A1 butyrophilin, subfamily 3, member A1
C17ORF53 chromosome 17 open reading frame 53
C17ORF85 chromosome 17 open reading frame 85
C21ORF2 chromosome 21 open reading frame 2
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC85C coiled-coil domain containing 85C
CDADC1 cytidine and dCMP deaminase domain containing 1
CFDP1 craniofacial development protein 1
COL3A1 collagen, type III, alpha 1
COL6A1 collagen, type VI, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
DCLRE1A DNA cross-link repair 1A
DZIP3 DAZ interacting zinc finger protein 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELMO2 engulfment and cell motility 2
EXOC5 exocyst complex component 5
FBN2 fibrillin 2
FLT3LG fms-related tyrosine kinase 3 ligand
GPR1 G protein-coupled receptor 1
HSDL2 hydroxysteroid dehydrogenase like 2
IL15RA interleukin 15 receptor, alpha
IRAK4 interleukin-1 receptor-associated kinase 4
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KDM4B lysine (K)-specific demethylase 4B
KIAA1109 KIAA1109
KIF5C kinesin family member 5C
KRIT1 KRIT1, ankyrin repeat containing
LMNB1 lamin B1
LOC57399 uncharacterized gastric protein ZA52P
MBTD1 mbt domain containing 1
METTL16 methyltransferase like 16
MIIP migration and invasion inhibitory protein
MMP13 matrix metallopeptidase 13
MNDA myeloid cell nuclear differentiation antigen
NF2 neurofibromin 2 (merlin)
NID1 nidogen 1
NIPBL Nipped-B homolog (Drosophila)
NNAT neuronatin
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAIP2B poly(A) binding protein interacting protein 2B
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PEX1 peroxisomal biogenesis factor 1
PKD2L2 polycystic kidney disease 2-like 2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POMT2 protein-O-mannosyltransferase 2
PRB1 proline-rich protein BstNI subfamily 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB2A RAB2A, member RAS oncogene family
RNF19B ring finger protein 19B
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL35A ribosomal protein L35a
RUNX1-IT1 RUNX1 intronic transcript 1
SARM1 sterile alpha and TIR motif containing 1
SIX3 SIX homeobox 3
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD5 SMAD family member 5
SS18 synovial sarcoma translocation, chromosome 18
STK16 serine/threonine kinase 16
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYT1 synaptotagmin I
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLE4 transducin-like enhancer of split 4
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM63A transmembrane protein 63A
TPMT thiopurine S-methyltransferase
TRAPPC13 trafficking protein particle complex 13
TRIM14 tripartite motif containing 14
UBAP2L ubiquitin associated protein 2-like
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZMYM5 zinc finger, MYM-type 5
ZNF117 zinc finger protein 117
ZNF165 zinc finger protein 165
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ADGRF1 adhesion G protein-coupled receptor F1
AGBL5 ATP/GTP binding protein-like 5
AKR1C3 aldo-keto reductase family 1, member C3
ALPK1 alpha-kinase 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
APOO apolipoprotein O
ASB6 ankyrin repeat and SOCS box containing 6
C11ORF80 chromosome 11 open reading frame 80
C19ORF40 chromosome 19 open reading frame 40
C19ORF54 chromosome 19 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CADPS2 Ca++-dependent secretion activator 2
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC94 coiled-coil domain containing 94
CCNT1 cyclin T1
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CLSPN claspin
CUL9 cullin 9
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DET1 de-etiolated homolog 1 (Arabidopsis)
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DLL3 delta-like 3 (Drosophila)
DOCK1 dedicator of cytokinesis 1
EDC3 enhancer of mRNA decapping 3
ENDOG endonuclease G
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM53B family with sequence similarity 53, member B
FIG4 FIG4 phosphoinositide 5-phosphatase
FKBPL FK506 binding protein like
FSTL3 follistatin-like 3 (secreted glycoprotein)
GRWD1 glutamate-rich WD repeat containing 1
HMHA1 histocompatibility (minor) HA-1
HOXC8 homeobox C8
IL7R interleukin 7 receptor
INF2 inverted formin, FH2 and WH2 domain containing
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCTD20 potassium channel tetramerization domain containing 20
KIAA0355 KIAA0355
KIFC1 kinesin family member C1
LZTR1 leucine-zipper-like transcription regulator 1
MAP1S microtubule-associated protein 1S
MEIS1 Meis homeobox 1
MFGE8 milk fat globule-EGF factor 8 protein
MKS1 Meckel syndrome, type 1
MPI mannose phosphate isomerase
MTMR12 myotubularin related protein 12
MYLK myosin light chain kinase
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NXN nucleoredoxin
ODF2 outer dense fiber of sperm tails 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PALB2 partner and localizer of BRCA2
PDZD2 PDZ domain containing 2
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLSCR4 phospholipid scramblase 4
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRAME preferentially expressed antigen in melanoma
PRKCD protein kinase C, delta
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM38 RNA binding motif protein 38
RNF121 ring finger protein 121
RPGR retinitis pigmentosa GTPase regulator
SDF2 stromal cell-derived factor 2
SELENBP1 selenium binding protein 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3BGR SH3 domain binding glutamate-rich protein
SIX1 SIX homeobox 1
SLC22A18 solute carrier family 22, member 18
SOBP sine oculis binding protein homolog (Drosophila)
SRBD1 S1 RNA binding domain 1
STBD1 starch binding domain 1
TDP1 tyrosyl-DNA phosphodiesterase 1
TIGD6 tigger transposable element derived 6
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM209 transmembrane protein 209
TMSB15B thymosin beta 15B
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TUBA3C tubulin, alpha 3c
TWF2 twinfilin actin binding protein 2
UBP1 upstream binding protein 1 (LBP-1a)
UBXN6 UBX domain protein 6
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR76 WD repeat domain 76
ZBTB24 zinc finger and BTB domain containing 24
ZBTB25 zinc finger and BTB domain containing 25
ZFHX3 zinc finger homeobox 3
ZNF770 zinc finger protein 770
ZNF813 zinc finger protein 813
ZNF862 zinc finger protein 862