drofenine-7129 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the drofenine-7129 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANAPC5 anaphase promoting complex subunit 5
APH1B APH1B gamma secretase subunit
APP amyloid beta (A4) precursor protein
ATXN7L1 ataxin 7-like 1
B3GAT3 beta-1,3-glucuronyltransferase 3
C9ORF114 chromosome 9 open reading frame 114
CD79B CD79b molecule, immunoglobulin-associated beta
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDRT1 CMT1A duplicated region transcript 1
COL5A1 collagen, type V, alpha 1
COQ6 coenzyme Q6 monooxygenase
CYR61 cysteine-rich, angiogenic inducer, 61
DENND2A DENN/MADD domain containing 2A
DGCR8 DGCR8 microprocessor complex subunit
DHCR7 7-dehydrocholesterol reductase
ECE1 endothelin converting enzyme 1
EML3 echinoderm microtubule associated protein like 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPS8L1 EPS8-like 1
ETAA1 Ewing tumor-associated antigen 1
FADS3 fatty acid desaturase 3
FAM69A family with sequence similarity 69, member A
FGFR2 fibroblast growth factor receptor 2
FST follistatin
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GPR176 G protein-coupled receptor 176
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2AJ histone cluster 1, H2aj
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IDS iduronate 2-sulfatase
IQCK IQ motif containing K
KDM4B lysine (K)-specific demethylase 4B
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT34 keratin 34, type I
LOC81691 exonuclease NEF-sp
LPP LIM domain containing preferred translocation partner in lipoma
LRRC41 leucine rich repeat containing 41
LRRK1 leucine-rich repeat kinase 1
MCL1 myeloid cell leukemia 1
MLH3 mutL homolog 3
MRPS11 mitochondrial ribosomal protein S11
MTSS1L metastasis suppressor 1-like
MUC1 mucin 1, cell surface associated
MUC8 mucin 8
MVK mevalonate kinase
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO9A myosin IXA
NCOA2 nuclear receptor coactivator 2
NNMT nicotinamide N-methyltransferase
NOLC1 nucleolar and coiled-body phosphoprotein 1
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2
NUMA1 nuclear mitotic apparatus protein 1
OSBPL3 oxysterol binding protein-like 3
PACS1 phosphofurin acidic cluster sorting protein 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PARVB parvin, beta
PDLIM7 PDZ and LIM domain 7 (enigma)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP5C protein phosphatase 5, catalytic subunit
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSIP1 PC4 and SFRS1 interacting protein 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PVR poliovirus receptor
RAB31 RAB31, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RANGAP1 Ran GTPase activating protein 1
RGS10 regulator of G-protein signaling 10
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SBF1 SET binding factor 1
SCAMP5 secretory carrier membrane protein 5
SCG5 secretogranin V
SETD8 SET domain containing (lysine methyltransferase) 8
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC38A7 solute carrier family 38, member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SOBP sine oculis binding protein homolog (Drosophila)
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
STOML1 stomatin (EPB72)-like 1
STS steroid sulfatase (microsomal), isozyme S
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYNJ2 synaptojanin 2
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TSPAN1 tetraspanin 1
TTC12 tetratricopeptide repeat domain 12
TTC23 tetratricopeptide repeat domain 23
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VWA8 von Willebrand factor A domain containing 8
WDR61 WD repeat domain 61
WNK1 WNK lysine deficient protein kinase 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFPL1 zinc finger protein-like 1
ZNF444 zinc finger protein 444
ZNF529 zinc finger protein 529

decreased expression

Symbol Name
ANG angiogenin, ribonuclease, RNase A family, 5
ANKRD36 ankyrin repeat domain 36
ANXA10 annexin A10
APH1A APH1A gamma secretase subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ASB13 ankyrin repeat and SOCS box containing 13
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BIRC3 baculoviral IAP repeat containing 3
C1ORF35 chromosome 1 open reading frame 35
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CEP170B centrosomal protein 170B
CEP83 centrosomal protein 83kDa
CHML choroideremia-like (Rab escort protein 2)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DBR1 debranching RNA lariats 1
DEAF1 DEAF1 transcription factor
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ETV4 ets variant 4
FAM131A family with sequence similarity 131, member A
FAM134C family with sequence similarity 134, member C
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FDXR ferredoxin reductase
FGD1 FYVE, RhoGEF and PH domain containing 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FSD1 fibronectin type III and SPRY domain containing 1
GAB2 GRB2-associated binding protein 2
GID4 GID complex subunit 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC5 histone deacetylase 5
HDAC9 histone deacetylase 9
HIRA histone cell cycle regulator
HLA-J major histocompatibility complex, class I, J (pseudogene)
IFT81 intraflagellar transport 81
IPO8 importin 8
IRF9 interferon regulatory factor 9
KCTD15 potassium channel tetramerization domain containing 15
KIAA0232 KIAA0232
KIAA0894 KIAA0894 protein
KIF18A kinesin family member 18A
KLC2 kinesin light chain 2
KLHL12 kelch-like family member 12
KLHL2 kelch-like family member 2
KPTN kaptin (actin binding protein)
LPAR6 lysophosphatidic acid receptor 6
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP9 microtubule-associated protein 9
MAST3 microtubule associated serine/threonine kinase 3
MON1B MON1 secretory trafficking family member B
MTMR14 myotubularin related protein 14
MYO1E myosin IE
NABP2 nucleic acid binding protein 2
NADSYN1 NAD synthetase 1
NHLRC2 NHL repeat containing 2
NINJ1 ninjurin 1
NINL ninein-like
NXPE3 neurexophilin and PC-esterase domain family, member 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PDIA3 protein disulfide isomerase family A, member 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PNRC1 proline-rich nuclear receptor coactivator 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PTK7 protein tyrosine kinase 7 (inactive)
RECQL4 RecQ protein-like 4
REV1 REV1, polymerase (DNA directed)
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC22A18 solute carrier family 22, member 18
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SPATA7 spermatogenesis associated 7
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STK25 serine/threonine kinase 25
STX1A syntaxin 1A (brain)
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D10B TBC1 domain family, member 10B
TENM4 teneurin transmembrane protein 4
TMEM2 transmembrane protein 2
TMEM254 transmembrane protein 254
TMEM8A transmembrane protein 8A
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TOR4A torsin family 4, member A
TSPAN12 tetraspanin 12
TUBA3C tubulin, alpha 3c
URM1 ubiquitin related modifier 1
XAB2 XPA binding protein 2
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP69B ZFP69 zinc finger protein B
ZMAT5 zinc finger, matrin-type 5
ZNF408 zinc finger protein 408
ZNF551 zinc finger protein 551