double-strand break repair via nonhomologous end joining Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear. (Gene Ontology, GO_0006303)
External Link http://amigo.geneontology.org/amigo/term/GO:0006303
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Genes

21 genes participating in the double-strand break repair via nonhomologous end joining biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
C9ORF142 chromosome 9 open reading frame 142
KDM2A lysine (K)-specific demethylase 2A
LIG1 ligase I, DNA, ATP-dependent
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
MLH1 mutL homolog 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
NHEJ1 nonhomologous end-joining factor 1
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLQ polymerase (DNA directed), theta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF19 pre-mRNA processing factor 19
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
SETMAR SET domain and mariner transposase fusion gene
SMC5 structural maintenance of chromosomes 5
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XRCC6BP1 XRCC6 binding protein 1