dominantnegative Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

181 genes co-occuring with the biological term dominantnegative in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACVR1 activin A receptor, type I
ADAM10 ADAM metallopeptidase domain 10
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB2 adrenoceptor beta 2, surface
AKAP12 A kinase (PRKA) anchor protein 12
AKAP9 A kinase (PRKA) anchor protein 9
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALX4 ALX homeobox 4
AOC3 amine oxidase, copper containing 3
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
AQP2 aquaporin 2 (collecting duct)
ARR3 arrestin 3, retinal (X-arrestin)
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATM ATM serine/threonine kinase
AXIN1 axin 1
BAX BCL2-associated X protein
BIRC5 baculoviral IAP repeat containing 5
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTK Bruton agammaglobulinemia tyrosine kinase
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCNDBP1 cyclin D-type binding-protein 1
CD44 CD44 molecule (Indian blood group)
CDC6 cell division cycle 6
CDH13 cadherin 13
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK2 checkpoint kinase 2
CHMP3 charged multivesicular body protein 3
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
COL10A1 collagen, type X, alpha 1
COL4A1 collagen, type IV, alpha 1
COL7A1 collagen, type VII, alpha 1
CPT2 carnitine palmitoyltransferase 2
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL5 cullin 5
DAPK1 death-associated protein kinase 1
DCP1A decapping mRNA 1A
DES desmin
DIAPH1 diaphanous-related formin 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLL1 delta-like 1 (Drosophila)
DSP desmoplakin
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EGR2 early growth response 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELOVL4 ELOVL fatty acid elongase 4
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
EYA1 EYA transcriptional coactivator and phosphatase 1
FADD Fas (TNFRSF6)-associated via death domain
FOXL2 forkhead box L2
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
GATA3 GATA binding protein 3
GCM2 glial cells missing homolog 2 (Drosophila)
GGT1 gamma-glutamyltransferase 1
GJA1 gap junction protein, alpha 1, 43kDa
GJB2 gap junction protein, beta 2, 26kDa
GLI2 GLI family zinc finger 2
GLRA1 glycine receptor, alpha 1
GNRHR gonadotropin-releasing hormone receptor
GSK3B glycogen synthase kinase 3 beta
GUCA1A guanylate cyclase activator 1A (retina)
HCST hematopoietic cell signal transducer
HELB helicase (DNA) B
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HSF1 heat shock transcription factor 1
HSPB1 heat shock 27kDa protein 1
IFNGR1 interferon gamma receptor 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IRAK1 interleukin-1 receptor-associated kinase 1
IRF3 interferon regulatory factor 3
IRF6 interferon regulatory factor 6
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK3 Janus kinase 3
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNK18 potassium channel, two pore domain subfamily K, member 18
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KLF6 Kruppel-like factor 6
LHX4 LIM homeobox 4
LRRK2 leucine-rich repeat kinase 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK3 mitogen-activated protein kinase 3
MED25 mediator complex subunit 25
MIR192 microRNA 192
MMP2 matrix metallopeptidase 2
MTMR3 myotubularin related protein 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
MYL7 myosin, light chain 7, regulatory
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
ORAI1 ORAI calcium release-activated calcium modulator 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PAX5 paired box 5
PHOX2B paired-like homeobox 2b
PKN2 protein kinase N2
PML promyelocytic leukemia
POLB polymerase (DNA directed), beta
POU1F1 POU class 1 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCD protein kinase C, delta
PRNP prion protein
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RANGRF RAN guanine nucleotide release factor
RARA retinoic acid receptor, alpha
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RET ret proto-oncogene
RHOA ras homolog family member A
RNF14 ring finger protein 14
RXFP1 relaxin/insulin-like family peptide receptor 1
S100A13 S100 calcium binding protein A13
SALL4 spalt-like transcription factor 4
SGK1 serum/glucocorticoid regulated kinase 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SKIL SKI-like proto-oncogene
SLC19A1 solute carrier family 19 (folate transporter), member 1
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOX18 SRY (sex determining region Y)-box 18
SPOP speckle-type POZ protein
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYCP3 synaptonemal complex protein 3
TERT telomerase reverse transcriptase
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFDP1 transcription factor Dp-1
TLR3 toll-like receptor 3
TNF tumor necrosis factor
TOR1B torsin family 1, member B (torsin B)
TP53 tumor protein p53
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TSC2 tuberous sclerosis 2
TSC22D1 TSC22 domain family, member 1
TSHR thyroid stimulating hormone receptor
TYROBP TYRO protein tyrosine kinase binding protein
UBE2C ubiquitin-conjugating enzyme E2C
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UMOD uromodulin
USF1 upstream transcription factor 1
USF2 upstream transcription factor 2, c-fos interacting
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VIM vimentin
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein
ZPBP zona pellucida binding protein