dna-directed rna polymerase ii, core complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. (Gene Ontology, GO_0005665)
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15 proteins localized to the dna-directed rna polymerase ii, core complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
URI1 URI1, prefoldin-like chaperone 0.663342
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 0.663342
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 0.663342
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.663342
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.663342
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.663342
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 0.663342
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.663342
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 0.663342
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 0.663342
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.663342
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 0.663342
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.663342
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 0.663342
ZNF768 zinc finger protein 768 0.03318