dna-dependent protein kinase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku. (Gene Ontology, GO_0070418)
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31 proteins co-occuring with the dna-dependent protein kinase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PRKDC protein kinase, DNA-activated, catalytic polypeptide 2.43507
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.9855
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 1.29692
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.25075
XRCC6BP1 XRCC6 binding protein 1 1.23975
DTNBP1 dystrobrevin binding protein 1 0.858933
LIG4 ligase IV, DNA, ATP-dependent 0.813028
RECQL4 RecQ protein-like 4 0.802479
NHEJ1 nonhomologous end-joining factor 1 0.769083
ATM ATM serine/threonine kinase 0.760887
WRN Werner syndrome, RecQ helicase-like 0.689451
DEAF1 DEAF1 transcription factor 0.689451
EME1 essential meiotic structure-specific endonuclease 1 0.655602
RECQL RecQ helicase-like 0.572994
H2AFX H2A histone family, member X 0.524294
DCLRE1C DNA cross-link repair 1C 0.460001
TP53 tumor protein p53 0.41143
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.361659
ERCC5 excision repair cross-complementation group 5 0.337751
MUS81 MUS81 structure-specific endonuclease subunit 0.334733
IL7R interleukin 7 receptor 0.284401
AMD1 adenosylmethionine decarboxylase 1 0.281453
MDC1 mediator of DNA-damage checkpoint 1 0.277038
GADD45A growth arrest and DNA-damage-inducible, alpha 0.221378
EGFR epidermal growth factor receptor 0.209513
UNG uracil-DNA glycosylase 0.208481
CLU clusterin 0.207108
PARD6A par-6 family cell polarity regulator alpha 0.198325
AICDA activation-induced cytidine deaminase 0.191135
HDAC3 histone deacetylase 3 0.179167
SRSF1 serine/arginine-rich splicing factor 1 0.157397