dna-(apurinic or apyrimidinic site) lyase activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. (Gene Ontology, GO_0003906)
External Link http://amigo.geneontology.org/amigo/term/GO:0003906
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Genes

12 genes performing the dna-(apurinic or apyrimidinic site) lyase activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APLF aprataxin and PNKP like factor
HMGA2 high mobility group AT-hook 2
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NTHL1 nth endonuclease III-like 1 (E. coli)
OGG1 8-oxoguanine DNA glycosylase
RPS3 ribosomal protein S3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1