dna integrity checkpoint Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes. (Gene Ontology, GO_0031570)
External Link http://amigo.geneontology.org/amigo/term/GO:0031570
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Genes

87 genes participating in the dna integrity checkpoint biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ATF2 activating transcription factor 2
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
BABAM1 BRISC and BRCA1 A complex member 1
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BRSK1 BR serine/threonine kinase 1
C10ORF90 chromosome 10 open reading frame 90
CCNA2 cyclin A2
CCND1 cyclin D1
CCNG1 cyclin G1
CDC14B cell division cycle 14B
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDT1 chromatin licensing and DNA replication factor 1
CEP63 centrosomal protein 63kDa
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CLOCK clock circadian regulator
CLSPN claspin
DNA2 DNA replication helicase/nuclease 2
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F1 E2F transcription factor 1
FAM175A family with sequence similarity 175, member A
FBXO31 F-box protein 31
FBXO6 F-box protein 6
FOXN3 forkhead box N3
FOXO4 forkhead box O4
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GIGYF2 GRB10 interacting GYF protein 2
H2AFX H2A histone family, member X
HINFP histone H4 transcription factor
HMGA2 high mobility group AT-hook 2
HUS1 HUS1 checkpoint homolog (S. pombe)
HUS1B HUS1 checkpoint homolog b (S. pombe)
IER3 immediate early response 3
INTS7 integrator complex subunit 7
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBD4 methyl-CpG binding domain protein 4
MDC1 mediator of DNA-damage checkpoint 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
NAE1 NEDD8 activating enzyme E1 subunit 1
NBN nibrin
NEK11 NIMA-related kinase 11
NEK6 NIMA-related kinase 6
PEA15 phosphoprotein enriched in astrocytes 15
PLK1 polo-like kinase 1
PLK5 polo-like kinase 5
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RAD9A RAD9 homolog A (S. pombe)
RAD9B RAD9 homolog B (S. pombe)
RBBP8 retinoblastoma binding protein 8
RFWD3 ring finger and WD repeat domain 3
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RPA2 replication protein A2, 32kDa
RPA4 replication protein A4, 30kDa
RPS27L ribosomal protein S27-like
SETMAR SET domain and mariner transposase fusion gene
STRA8 stimulated by retinoic acid 8
SYF2 SYF2 pre-mRNA-splicing factor
TAOK1 TAO kinase 1
TAOK2 TAO kinase 2
TAOK3 TAO kinase 3
TICRR TOPBP1-interacting checkpoint and replication regulator
TIPIN TIMELESS interacting protein
TIPRL TOR signaling pathway regulator
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
UIMC1 ubiquitin interaction motif containing 1
USP28 ubiquitin specific peptidase 28
WAC WW domain containing adaptor with coiled-coil
XPC xeroderma pigmentosum, complementation group C
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF830 zinc finger protein 830