dl-alpha tocopherol-4961 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the dl-alpha tocopherol-4961 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADAM8 ADAM metallopeptidase domain 8
ALDOB aldolase B, fructose-bisphosphate
ARHGAP33 Rho GTPase activating protein 33
ARHGAP44 Rho GTPase activating protein 44
ATP2A3 ATPase, Ca++ transporting, ubiquitous
AUTS2 autism susceptibility candidate 2
C11ORF63 chromosome 11 open reading frame 63
C14ORF79 chromosome 14 open reading frame 79
C17ORF59 chromosome 17 open reading frame 59
CAMK1 calcium/calmodulin-dependent protein kinase I
CASKIN2 CASK interacting protein 2
CAV2 caveolin 2
CCL27 chemokine (C-C motif) ligand 27
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDADC1 cytidine and dCMP deaminase domain containing 1
CFAP45 cilia and flagella associated protein 45
CLCN7 chloride channel, voltage-sensitive 7
CLIC2 chloride intracellular channel 2
CLTA clathrin, light chain A
COL14A1 collagen, type XIV, alpha 1
COL1A2 collagen, type I, alpha 2
COL6A1 collagen, type VI, alpha 1
CUL9 cullin 9
DAPK3 death-associated protein kinase 3
DDIT3 DNA-damage-inducible transcript 3
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DHRS12 dehydrogenase/reductase (SDR family) member 12
DLG5 discs, large homolog 5 (Drosophila)
DLK2 delta-like 2 homolog (Drosophila)
DOCK6 dedicator of cytokinesis 6
DST dystonin
EFR3B EFR3 homolog B (S. cerevisiae)
FAM134B family with sequence similarity 134, member B
FRMD4B FERM domain containing 4B
GPC1 glypican 1
GPC3 glypican 3
GRM8 glutamate receptor, metabotropic 8
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HIST1H4E histone cluster 1, H4e
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HOMER3 homer scaffolding protein 3
HOXB2 homeobox B2
HPX hemopexin
IDS iduronate 2-sulfatase
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDM4B lysine (K)-specific demethylase 4B
KRT19P2 keratin 19 pseudogene 2
LEF1 lymphoid enhancer-binding factor 1
LINC00597 long intergenic non-protein coding RNA 597
LMF2 lipase maturation factor 2
LOC399491
LOX lysyl oxidase
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAST3 microtubule associated serine/threonine kinase 3
MCAM melanoma cell adhesion molecule
MFAP3L microfibrillar-associated protein 3-like
MRPS18C mitochondrial ribosomal protein S18C
MTRF1L mitochondrial translational release factor 1-like
MUC3A mucin 3A, cell surface associated
MXD4 MAX dimerization protein 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO1F myosin IF
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF2 neurofibromin 2 (merlin)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLGN1 neuroligin 1
OGFR opioid growth factor receptor
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PCDHGB5 protocadherin gamma subfamily B, 5
PITX1 paired-like homeodomain 1
PLAU plasminogen activator, urokinase
PTDSS2 phosphatidylserine synthase 2
PTRF polymerase I and transcript release factor
RAB6A RAB6A, member RAS oncogene family
RNF122 ring finger protein 122
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
SCAPER S-phase cyclin A-associated protein in the ER
SCN1B sodium channel, voltage gated, type I beta subunit
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SND1-IT1 SND1 intronic transcript 1
STIM1 stromal interaction molecule 1
TLR8 toll-like receptor 8
TMCC2 transmembrane and coiled-coil domain family 2
TNS1 tensin 1
TRAF3IP3 TRAF3 interacting protein 3
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
ZBED4 zinc finger, BED-type containing 4
ZNF609 zinc finger protein 609
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BCL2L2 BCL2-like 2
BEX4 brain expressed, X-linked 4
C21ORF91 chromosome 21 open reading frame 91
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC132 coiled-coil domain containing 132
CCNE1 cyclin E1
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CEP97 centrosomal protein 97kDa
CIDEB cell death-inducing DFFA-like effector b
CLDN9 claudin 9
COCH cochlin
CRBN cereblon
CTNNBIP1 catenin, beta interacting protein 1
DEAF1 DEAF1 transcription factor
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
FGD6 FYVE, RhoGEF and PH domain containing 6
FPGS folylpolyglutamate synthase
FRS2 fibroblast growth factor receptor substrate 2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GEMIN8 gem (nuclear organelle) associated protein 8
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GID4 GID complex subunit 4
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPX2 glutathione peroxidase 2
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST2H2AA3 histone cluster 2, H2aa3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGSF1 immunoglobulin superfamily, member 1
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ITPKB inositol-trisphosphate 3-kinase B
KCTD20 potassium channel tetramerization domain containing 20
LHX6 LIM homeobox 6
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MBTD1 mbt domain containing 1
MDM4 MDM4, p53 regulator
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVD mevalonate (diphospho) decarboxylase
NDRG4 NDRG family member 4
NPIPB15 nuclear pore complex interacting protein family, member B15
NPY1R neuropeptide Y receptor Y1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLA2G12A phospholipase A2, group XIIA
PLCD1 phospholipase C, delta 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
PTK6 protein tyrosine kinase 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
R3HCC1L R3H domain and coiled-coil containing 1-like
RBM42 RNA binding motif protein 42
REEP1 receptor accessory protein 1
RPAP1 RNA polymerase II associated protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SOWAHC sosondowah ankyrin repeat domain family member C
SRPX sushi-repeat containing protein, X-linked
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYCP2 synaptonemal complex protein 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TIGAR TP53 induced glycolysis regulatory phosphatase
TRABD TraB domain containing
TSPAN1 tetraspanin 1
UBXN8 UBX domain protein 8
ULBP2 UL16 binding protein 2
VGF VGF nerve growth factor inducible
WASF1 WAS protein family, member 1
ZBTB48 zinc finger and BTB domain containing 48
ZBTB6 zinc finger and BTB domain containing 6
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZIC1 Zic family member 1
ZNF14 zinc finger protein 14
ZNF16 zinc finger protein 16
ZNF165 zinc finger protein 165
ZNF33B zinc finger protein 33B
ZNF787 zinc finger protein 787
ZNF862 zinc finger protein 862
ZSCAN31 zinc finger and SCAN domain containing 31