dl-alpha tocopherol-3256 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the dl-alpha tocopherol-3256 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
AHNAK AHNAK nucleoprotein
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASPH aspartate beta-hydroxylase
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BBS9 Bardet-Biedl syndrome 9
BCL2 B-cell CLL/lymphoma 2
BHLHE41 basic helix-loop-helix family, member e41
BMP5 bone morphogenetic protein 5
BTBD7 BTB (POZ) domain containing 7
C8ORF44 chromosome 8 open reading frame 44
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CDC25A cell division cycle 25A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL17A1 collagen, type XVII, alpha 1
CORO7 coronin 7
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCAF15 DDB1 and CUL4 associated factor 15
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DTNA dystrobrevin, alpha
EDRF1 erythroid differentiation regulatory factor 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELL elongation factor RNA polymerase II
FANCI Fanconi anemia, complementation group I
FH fumarate hydratase
FKBP8 FK506 binding protein 8, 38kDa
FRMD4A FERM domain containing 4A
FSCN1 fascin actin-bundling protein 1
FURIN furin (paired basic amino acid cleaving enzyme)
GPER1 G protein-coupled estrogen receptor 1
H1FX H1 histone family, member X
HCFC1 host cell factor C1
HLA-DOA major histocompatibility complex, class II, DO alpha
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
JRK Jrk homolog (mouse)
KAT6A K(lysine) acetyltransferase 6A
KIAA0319L KIAA0319-like
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC647070 uncharacterized LOC647070
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LTBP4 latent transforming growth factor beta binding protein 4
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK7 mitogen-activated protein kinase 7
MPZL1 myelin protein zero-like 1
MRC2 mannose receptor, C type 2
MVP major vault protein
MXD4 MAX dimerization protein 4
MYLK myosin light chain kinase
MYOF myoferlin
NBL1 neuroblastoma 1, DAN family BMP antagonist
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF1 neurofibromin 1
NFIB nuclear factor I/B
NPHP1 nephronophthisis 1 (juvenile)
NRF1 nuclear respiratory factor 1
NRSN2 neurensin 2
NUMA1 nuclear mitotic apparatus protein 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
OBSL1 obscurin-like 1
OSBPL10 oxysterol binding protein-like 10
PALM paralemmin
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE8B phosphodiesterase 8B
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POFUT1 protein O-fucosyltransferase 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
RBM48 RNA binding motif protein 48
RGS12 regulator of G-protein signaling 12
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF17 ring finger protein 17
RUNDC3B RUN domain containing 3B
SFTPC surfactant protein C
SIM2 single-minded family bHLH transcription factor 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPTBN1 spectrin, beta, non-erythrocytic 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TMEM120B transmembrane protein 120B
TMOD1 tropomodulin 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
VLDLR very low density lipoprotein receptor
ZBTB1 zinc finger and BTB domain containing 1
ZFHX4 zinc finger homeobox 4
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF532 zinc finger protein 532
ZNF589 zinc finger protein 589
ZNF710 zinc finger protein 710
ZNF768 zinc finger protein 768
ZNF862 zinc finger protein 862
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACSF2 acyl-CoA synthetase family member 2
ADAM15 ADAM metallopeptidase domain 15
ADGRG2 adhesion G protein-coupled receptor G2
AGMAT agmatine ureohydrolase (agmatinase)
APOD apolipoprotein D
ARMCX2 armadillo repeat containing, X-linked 2
ARRB1 arrestin, beta 1
AUTS2 autism susceptibility candidate 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BBC3 BCL2 binding component 3
C11ORF30 chromosome 11 open reading frame 30
C19ORF73 chromosome 19 open reading frame 73
C1ORF105 chromosome 1 open reading frame 105
C2ORF27A chromosome 2 open reading frame 27A
C9ORF9 chromosome 9 open reading frame 9
CBR3 carbonyl reductase 3
CBX8 chromobox homolog 8
CCDC85C coiled-coil domain containing 85C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CERS4 ceramide synthase 4
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFCAB2 EF-hand calcium binding domain 2
EMID1 EMI domain containing 1
ERCC4 excision repair cross-complementation group 4
FAM131A family with sequence similarity 131, member A
FAM188A family with sequence similarity 188, member A
FKBP5 FK506 binding protein 5
FUZ fuzzy planar cell polarity protein
GAMT guanidinoacetate N-methyltransferase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR27 G protein-coupled receptor 27
HIST1H2AM histone cluster 1, H2am
HIST1H2BO histone cluster 1, H2bo
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-J major histocompatibility complex, class I, J (pseudogene)
HPN hepsin
ING4 inhibitor of growth family, member 4
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
JUNB jun B proto-oncogene
KCTD20 potassium channel tetramerization domain containing 20
KLF2 Kruppel-like factor 2
LRP5L low density lipoprotein receptor-related protein 5-like
LY6D lymphocyte antigen 6 complex, locus D
LYRM9 LYR motif containing 9
MBTPS2 membrane-bound transcription factor peptidase, site 2
MGC12488
MVD mevalonate (diphospho) decarboxylase
NCS1 neuronal calcium sensor 1
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
ONECUT2 one cut homeobox 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVOL1 ovo-like zinc finger 1
PDE12 phosphodiesterase 12
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPAP2C phosphatidic acid phosphatase type 2C
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PVRL3 poliovirus receptor-related 3
RAB3D RAB3D, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFTN1 raftlin, lipid raft linker 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS17P5 ribosomal protein S17 pseudogene 5
SCN1B sodium channel, voltage gated, type I beta subunit
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRT2 sirtuin 2
SLC12A8 solute carrier family 12, member 8
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SPAG7 sperm associated antigen 7
SPRYD7 SPRY domain containing 7
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK25 serine/threonine kinase 25
TAOK1 TAO kinase 1
TMC7 transmembrane channel-like 7
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNC93B1 unc-93 homolog B1 (C. elegans)
USB1 U6 snRNA biogenesis 1
VEGFB vascular endothelial growth factor B
WDR91 WD repeat domain 91
ZBTB22 zinc finger and BTB domain containing 22
ZMAT5 zinc finger, matrin-type 5
ZNF211 zinc finger protein 211
ZNF652 zinc finger protein 652