dl-alpha tocopherol-1320 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the dl-alpha tocopherol-1320 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABHD6 abhydrolase domain containing 6
ACOX3 acyl-CoA oxidase 3, pristanoyl
AKAP11 A kinase (PRKA) anchor protein 11
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ANKRD26 ankyrin repeat domain 26
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AXIN1 axin 1
AZU1 azurocidin 1
BAG4 BCL2-associated athanogene 4
BCR breakpoint cluster region
BPI bactericidal/permeability-increasing protein
C16ORF59 chromosome 16 open reading frame 59
C1ORF109 chromosome 1 open reading frame 109
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CIDEC cell death-inducing DFFA-like effector c
CPM carboxypeptidase M
CYTH4 cytohesin 4
DEDD death effector domain containing
DFNA5 deafness, autosomal dominant 5
DLG4 discs, large homolog 4 (Drosophila)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DUS2 dihydrouridine synthase 2
EXOC7 exocyst complex component 7
FAM188A family with sequence similarity 188, member A
FAM63B family with sequence similarity 63, member B
FBXL18 F-box and leucine-rich repeat protein 18
FCAR Fc fragment of IgA receptor
FSCN1 fascin actin-bundling protein 1
FUZ fuzzy planar cell polarity protein
G6PC3 glucose 6 phosphatase, catalytic, 3
GLCE glucuronic acid epimerase
GM2A GM2 ganglioside activator
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HAB1 B1 for mucin
HIPK3 homeodomain interacting protein kinase 3
HIST1H2AJ histone cluster 1, H2aj
HLA-DMA major histocompatibility complex, class II, DM alpha
ITGB4 integrin, beta 4
JUND jun D proto-oncogene
KCTD2 potassium channel tetramerization domain containing 2
KIAA0319L KIAA0319-like
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LZTR1 leucine-zipper-like transcription regulator 1
MAP4 microtubule-associated protein 4
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAST2 microtubule associated serine/threonine kinase 2
MIIP migration and invasion inhibitory protein
MSRB2 methionine sulfoxide reductase B2
MVK mevalonate kinase
MYH15 myosin, heavy chain 15
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NFS1 NFS1 cysteine desulfurase
OGFR opioid growth factor receptor
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP12 poly (ADP-ribose) polymerase family, member 12
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PBLD phenazine biosynthesis-like protein domain containing
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PECR peroxisomal trans-2-enoyl-CoA reductase
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLCG1 phospholipase C, gamma 1
PPARD peroxisome proliferator-activated receptor delta
PTK2B protein tyrosine kinase 2 beta
RASA3 RAS p21 protein activator 3
RPL10 ribosomal protein L10
RPL13P5 ribosomal protein L13 pseudogene 5
SELPLG selectin P ligand
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SGSM3 small G protein signaling modulator 3
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMYD2 SET and MYND domain containing 2
SPATA2 spermatogenesis associated 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STBD1 starch binding domain 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TFIP11 tuftelin interacting protein 11
TMEM180 transmembrane protein 180
TMEM231 transmembrane protein 231
TPR translocated promoter region, nuclear basket protein
TTLL1 tubulin tyrosine ligase-like family member 1
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UNC93B1 unc-93 homolog B1 (C. elegans)
VEGFB vascular endothelial growth factor B
ZBTB43 zinc finger and BTB domain containing 43
ZDHHC17 zinc finger, DHHC-type containing 17
ZNF254 zinc finger protein 254
ZNF473 zinc finger protein 473
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADTRP androgen-dependent TFPI-regulating protein
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOL6 apolipoprotein L, 6
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASB6 ankyrin repeat and SOCS box containing 6
BATF basic leucine zipper transcription factor, ATF-like
BTBD18 BTB (POZ) domain containing 18
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C21ORF91 chromosome 21 open reading frame 91
C2ORF49 chromosome 2 open reading frame 49
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CCNT1 cyclin T1
CDADC1 cytidine and dCMP deaminase domain containing 1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CNR2 cannabinoid receptor 2 (macrophage)
CORO7 coronin 7
CSRNP2 cysteine-serine-rich nuclear protein 2
CTSO cathepsin O
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DTX4 deltex 4, E3 ubiquitin ligase
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV4 ets variant 4
FAM114A1 family with sequence similarity 114, member A1
FGL2 fibrinogen-like 2
FHIT fragile histidine triad
FKBP9 FK506 binding protein 9, 63 kDa
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GTF2IRD1 GTF2I repeat domain containing 1
HIST1H1E histone cluster 1, H1e
KAT2A K(lysine) acetyltransferase 2A
KLHDC4 kelch domain containing 4
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRK1 leucine-rich repeat kinase 1
MED22 mediator complex subunit 22
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MLYCD malonyl-CoA decarboxylase
MRPS34 mitochondrial ribosomal protein S34
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYL5 myosin, light chain 5, regulatory
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSUN3 NOP2/Sun domain family, member 3
NT5M 5',3'-nucleotidase, mitochondrial
PEMT phosphatidylethanolamine N-methyltransferase
PEX26 peroxisomal biogenesis factor 26
PLA2G15 phospholipase A2, group XV
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSKH1 protein serine kinase H1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBM47 RNA binding motif protein 47
RCL1 RNA terminal phosphate cyclase-like 1
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
SAMD9 sterile alpha motif domain containing 9
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIDT1 SID1 transmembrane family, member 1
SLC12A9 solute carrier family 12, member 9
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SP140L SP140 nuclear body protein-like
STX1A syntaxin 1A (brain)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN2 tectonic family member 2
TGM5 transglutaminase 5
THEM6 thioesterase superfamily member 6
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM134 transmembrane protein 134
TMEM160 transmembrane protein 160
TMEM62 transmembrane protein 62
TRABD TraB domain containing
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPS1 trichorhinophalangeal syndrome I
TSPAN32 tetraspanin 32
TXLNG taxilin gamma
UNC119B unc-119 homolog B (C. elegans)
WDR91 WD repeat domain 91
XAB2 XPA binding protein 2
ZC4H2 zinc finger, C4H2 domain containing
ZNF230 zinc finger protein 230
ZNF250 zinc finger protein 250
ZNF280D zinc finger protein 280D
ZNF35 zinc finger protein 35
ZNF354A zinc finger protein 354A
ZNF552 zinc finger protein 552
ZNF8 zinc finger protein 8
ZSCAN16 zinc finger and SCAN domain containing 16
ZW10 zw10 kinetochore protein