disease of cellular proliferation Gene Set

Dataset DISEASES Curated Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A disease that is characterized by abnormally rapid cell division. (Human Disease Ontology, DOID_14566)
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Genes

327 genes involed in the disease disease of cellular proliferation from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AFF1 AF4/FMR2 family, member 1
AFF4 AF4/FMR2 family, member 4
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGR2 anterior gradient 2
AKAP13 A kinase (PRKA) anchor protein 13
AKIP1 A kinase (PRKA) interacting protein 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALK anaplastic lymphoma receptor tyrosine kinase
APC adenomatous polyposis coli
AR androgen receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGAP26 Rho GTPase activating protein 26
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ASXL2 additional sex combs like transcriptional regulator 2
ATF1 activating transcription factor 1
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AXIN1 axin 1
AXL AXL receptor tyrosine kinase
BARD1 BRCA1 associated RING domain 1
BCAS3 breast carcinoma amplified sequence 3
BCAS4 breast carcinoma amplified sequence 4
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCL9 B-cell CLL/lymphoma 9
BCR breakpoint cluster region
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRD7 bromodomain containing 7
BRI3BP BRI3 binding protein
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BRMS1 breast cancer metastasis suppressor 1
BTG1 B-cell translocation gene 1, anti-proliferative
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CALR calreticulin
CARS cysteinyl-tRNA synthetase
CBFB core-binding factor, beta subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC6 coiled-coil domain containing 6
CCND1 cyclin D1
CCNL1 cyclin L1
CDC73 cell division cycle 73
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDT1 chromatin licensing and DNA replication factor 1
CHD5 chromodomain helicase DNA binding protein 5
CHEK2 checkpoint kinase 2
CMC4 C-x(9)-C motif containing 4
CREB3L2 cAMP responsive element binding protein 3-like 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSF1R colony stimulating factor 1 receptor
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTCF CCCTC-binding factor (zinc finger protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYLD cylindromatosis (turban tumor syndrome)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAB2IP DAB2 interacting protein
DCC DCC netrin 1 receptor
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
DDIT3 DNA-damage-inducible transcript 3
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEK DEK proto-oncogene
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DMBT1 deleted in malignant brain tumors 1
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27
DOCK4 dedicator of cytokinesis 4
ECT2 epithelial cell transforming 2
EGFR epidermal growth factor receptor
ELAC2 elaC ribonuclease Z 2
ELF4 E74-like factor 4 (ets domain transcription factor)
ELL elongation factor RNA polymerase II
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHB2 EPH receptor B2
EPS15 epidermal growth factor receptor pathway substrate 15
ERBB2 erb-b2 receptor tyrosine kinase 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV1 ets variant 1
ETV4 ets variant 4
ETV6 ets variant 6
EVI2A ecotropic viral integration site 2A
EVI2B ecotropic viral integration site 2B
EWSR1 EWS RNA-binding protein 1
FAM126A family with sequence similarity 126, member A
FAM3C family with sequence similarity 3, member C
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FER fer (fps/fes related) tyrosine kinase
FES FES proto-oncogene, tyrosine kinase
FEV FEV (ETS oncogene family)
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGR FGR proto-oncogene, Src family tyrosine kinase
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FOXP1 forkhead box P1
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FRK fyn-related Src family tyrosine kinase
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUS FUS RNA binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GAS7 growth arrest-specific 7
GFI1B growth factor independent 1B transcription repressor
GLI1 GLI family zinc finger 1
GMPS guanine monphosphate synthase
GNAS GNAS complex locus
HCK HCK proto-oncogene, Src family tyrosine kinase
HIC1 hypermethylated in cancer 1
HLF hepatic leukemia factor
HMGA2 high mobility group AT-hook 2
HOPX HOP homeobox
HOXA9 homeobox A9
HRAS Harvey rat sarcoma viral oncogene homolog
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IL2 interleukin 2
ING1 inhibitor of growth family, member 1
ING4 inhibitor of growth family, member 4
IRF1 interferon regulatory factor 1
JAK2 Janus kinase 2
JAZF1 JAZF zinc finger 1
JUN jun proto-oncogene
KAT6A K(lysine) acetyltransferase 6A
KCTD11 potassium channel tetramerization domain containing 11
KDSR 3-ketodihydrosphingosine reductase
KIF1B kinesin family member 1B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LCK LCK proto-oncogene, Src family tyrosine kinase
LETMD1 LETM1 domain containing 1
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LHX4 LIM homeobox 4
LIMD1 LIM domains containing 1
LITAF lipopolysaccharide-induced TNF factor
LMO1 LIM domain only 1 (rhombotin 1)
LMO2 LIM domain only 2 (rhombotin-like 1)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MCC mutated in colorectal cancers
MCF2 MCF.2 cell line derived transforming sequence
MCF2L MCF.2 cell line derived transforming sequence-like
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDS2 myelodysplastic syndrome 2 translocation associated
MECOM MDS1 and EVI1 complex locus
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MKL1 megakaryoblastic leukemia (translocation) 1
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MPL MPL proto-oncogene, thrombopoietin receptor
MTCP1 mature T-cell proliferation 1
MXI1 MAX interactor 1, dimerization protein
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH11 myosin, heavy chain 11, smooth muscle
NBN nibrin
NCKIPSD NCK interacting protein with SH3 domain
NCOA1 nuclear receptor coactivator 1
NCOA4 nuclear receptor coactivator 4
NDRG2 NDRG family member 2
NET1 neuroepithelial cell transforming 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF2 neurofibromin 2 (merlin)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NKX3-1 NK3 homeobox 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSD1 nuclear receptor binding SET domain protein 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUP214 nucleoporin 214kDa
OLIG2 oligodendrocyte lineage transcription factor 2
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PALB2 partner and localizer of BRCA2
PARK7 parkinson protein 7
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX3 paired box 3
PAX5 paired box 5
PAX7 paired box 7
PBX1 pre-B-cell leukemia homeobox 1
PCM1 pericentriolar material 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFB platelet-derived growth factor beta polypeptide
PDGFD platelet derived growth factor D
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PHB prohibitin
PHOX2B paired-like homeobox 2b
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PLAG1 pleiomorphic adenoma gene 1
PML promyelocytic leukemia
POU2AF1 POU class 2 associating factor 1
PRCC papillary renal cell carcinoma (translocation-associated)
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCI protein kinase C, iota
PTEN phosphatase and tensin homolog
PTTG1 pituitary tumor-transforming 1
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB8A RAB8A, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RB1 retinoblastoma 1
RBM15 RNA binding motif protein 15
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RET ret proto-oncogene
RHOA ras homolog family member A
RNF213 ring finger protein 213
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SALL4 spalt-like transcription factor 4
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SEC31A SEC31 homolog A (S. cerevisiae)
SET SET nuclear proto-oncogene
SH3GL1 SH3-domain GRB2-like 1
SIRT4 sirtuin 4
SKI SKI proto-oncogene
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPI1 Spi-1 proto-oncogene
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SS18 synovial sarcoma translocation, chromosome 18
SSX1 synovial sarcoma, X breakpoint 1
SSX2 synovial sarcoma, X breakpoint 2
SSX2B synovial sarcoma, X breakpoint 2B
STIL SCL/TAL1 interrupting locus
STK11 serine/threonine kinase 11
STYK1 serine/threonine/tyrosine kinase 1
SUZ12 SUZ12 polycomb repressive complex 2 subunit
T T, brachyury homolog (mouse)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAL1 T-cell acute lymphocytic leukemia 1
TAL2 T-cell acute lymphocytic leukemia 2
TBC1D3 TBC1 domain family, member 3
TBC1D3B TBC1 domain family, member 3B
TBC1D3F TBC1 domain family, member 3F
TBRG1 transforming growth factor beta regulator 1
TCF3 transcription factor 3
TCL1A T-cell leukemia/lymphoma 1A
TCTA T-cell leukemia translocation altered
TET2 tet methylcytosine dioxygenase 2
TFE3 transcription factor binding to IGHM enhancer 3
TFG TRK-fused gene
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
THPO thrombopoietin
TLX1 T-cell leukemia homeobox 1
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TP73 tumor protein p73
TPM3 tropomyosin 3
TPR translocated promoter region, nuclear basket protein
TRIM24 tripartite motif containing 24
TRIM27 tripartite motif containing 27
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TXNIP thioredoxin interacting protein
UFL1 UFM1-specific ligase 1
URI1 URI1, prefoldin-like chaperone
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP6 ubiquitin specific peptidase 6
VAV1 vav 1 guanine nucleotide exchange factor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WDR11 WD repeat domain 11
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WISP1 WNT1 inducible signaling pathway protein 1
WNT1 wingless-type MMTV integration site family, member 1
WNT3 wingless-type MMTV integration site family, member 3
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
WWTR1 WW domain containing transcription regulator 1
XAF1 XIAP associated factor 1
YAP1 Yes-associated protein 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZBTB16 zinc finger and BTB domain containing 16
ZBTB7C zinc finger and BTB domain containing 7C
ZDHHC17 zinc finger, DHHC-type containing 17
ZFYVE19 zinc finger, FYVE domain containing 19
ZMYND11 zinc finger, MYND-type containing 11
ZNF320 zinc finger protein 320
ZNF521 zinc finger protein 521