disease by infectious agent Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions. (Human Disease Ontology, DOID_0050117)
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Genes

150 genes associated with the disease disease by infectious agent in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
LACC1 laccase (multicopper oxidoreductase) domain containing 1 2.23329
SNX20 sorting nexin 20 2.03954
HLA-C major histocompatibility complex, class I, C 1.89624
MICA MHC class I polypeptide-related sequence A 1.88602
HBD hemoglobin, delta 1.70133
IFNL3 interferon, lambda 3 1.70133
HBB hemoglobin, beta 1.70133
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.58223
DDRGK1 DDRGK domain containing 1 1.55692
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.43016
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.42422
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 1.41921
CFB complement factor B 1.24299
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.20753
RIPK2 receptor-interacting serine-threonine kinase 2 1.17894
OR51F1 olfactory receptor, family 51, subfamily F, member 1 (gene/pseudogene) 1.14929
MMP26 matrix metallopeptidase 26 1.14929
POU5F1 POU class 5 homeobox 1 1.12703
ADGB androglobin 0.987984
OR51B5 olfactory receptor, family 51, subfamily B, member 5 0.978353
DEPDC5 DEP domain containing 5 0.965481
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.965481
CFHR3 complement factor H-related 3 0.916033
WT1 Wilms tumor 1 0.774217
C1ORF141 chromosome 1 open reading frame 141 0.774217
OR51V1 olfactory receptor, family 51, subfamily V, member 1 0.7623
MICB MHC class I polypeptide-related sequence B 0.7623
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.69843
CYLD cylindromatosis (turban tumor syndrome) 0.69843
PLCE1 phospholipase C, epsilon 1 0.682635
RBBP8 retinoblastoma binding protein 8 0.544585
C6ORF15 chromosome 6 open reading frame 15 0.52461
HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene) 0.486425
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.486425
HLA-J major histocompatibility complex, class I, J (pseudogene) 0.486425
RYR3 ryanodine receptor 3 0.464771
SASH1 SAM and SH3 domain containing 1 0.4215
ARHGAP20 Rho GTPase activating protein 20 0.414708
HCRTR2 hypocretin (orexin) receptor 2 0.403461
USP26 ubiquitin specific peptidase 26 0.368757
GRM5 glutamate receptor, metabotropic 5 0.345945
ZNRD1 zinc ribbon domain containing 1 0.345945
LOC648987 uncharacterized LOC648987 0.327313
NBEA neurobeachin 0.327313
ASB17 ankyrin repeat and SOCS box containing 17 0.327313
NPS neuropeptide S 0.327313
TSRM zinc finger domain-related protein TSRM 0.327313
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.311576
SPATA3 spermatogenesis associated 3 0.311576
CDH13 cadherin 13 0.311576
DGKI diacylglycerol kinase, iota 0.297866
RPL10L ribosomal protein L10-like 0.297866
PRMT6 protein arginine methyltransferase 6 0.297866
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 0.274608
GLTSCR1 glioma tumor suppressor candidate region gene 1 0.274608
RP1 retinitis pigmentosa 1 (autosomal dominant) 0.264872
GRM8 glutamate receptor, metabotropic 8 0.264872
EFCAB14 EF-hand calcium binding domain 14 0.256228
C6ORF48 chromosome 6 open reading frame 48 0.256228
MCM8 minichromosome maintenance complex component 8 0.256228
STXBP5 syntaxin binding protein 5 (tomosyn) 0.256228
ZNF804A zinc finger protein 804A 0.256228
EPHA5 EPH receptor A5 0.256228
WDR59 WD repeat domain 59 0.256228
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.256228
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 0.256228
HIST1H3H histone cluster 1, H3h 0.256228
OLFM1 olfactomedin 1 0.256228
ADAM18 ADAM metallopeptidase domain 18 0.197766
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.197766
DRGX dorsal root ganglia homeobox 0.197766
KCNMB3P1 potassium channel subfamily M regulatory beta subunit 3 pseudogene 1 0.197766
RGS2 regulator of G-protein signaling 2 0.197766
EYS eyes shut homolog (Drosophila) 0.197766
MAST4 microtubule associated serine/threonine kinase family member 4 0.197766
PARD3B par-3 family cell polarity regulator beta 0.197766
MARVELD3 MARVEL domain containing 3 0.197766
RFPL1 ret finger protein-like 1 0.197766
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.197766
WDR27 WD repeat domain 27 0.197766
DUSP14 dual specificity phosphatase 14 0.15771
HLA-B major histocompatibility complex, class I, B 0.15771
AOAH acyloxyacyl hydrolase (neutrophil) 0.15771
SCG2 secretogranin II 0.15771
C3ORF70 chromosome 3 open reading frame 70 0.15771
TNXB tenascin XB 0.15771
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 0.15771
EVI5L ecotropic viral integration site 5-like 0.126165
RXRG retinoid X receptor, gamma 0.126165
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 0.126165
PABPC1 poly(A) binding protein, cytoplasmic 1 0.126165
ZNF229 zinc finger protein 229 0.126165
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.100789
HBE1 hemoglobin, epsilon 1 0.100789
MUC21 mucin 21, cell surface associated 0.100789
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.100789
GPC5 glypican 5 0.100789
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.100789
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.100789
XPO1 exportin 1 0.100789
HBG2 hemoglobin, gamma G 0.100789
NAV2 neuron navigator 2 0.080593
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.080593
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.080593
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 0.080593
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.080593
HSP90AA4P heat shock protein 90kDa alpha (cytosolic), class A member 4, pseudogene 0.080593
TMEM64 transmembrane protein 64 0.080593
ZFP90 ZFP90 zinc finger protein 0.080593
ZDHHC19 zinc finger, DHHC-type containing 19 0.064973
EPHA7 EPH receptor A7 0.064973
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.064973
TET2 tet methylcytosine dioxygenase 2 0.064973
HMGXB3 HMG box domain containing 3 0.064973
DNASE2B deoxyribonuclease II beta 0.064973
AK9 adenylate kinase 9 0.064973
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.064973
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.064973
OR51E2 olfactory receptor, family 51, subfamily E, member 2 0.064973
SLCO5A1 solute carrier organic anion transporter family, member 5A1 0.064973
PSORS1C1 psoriasis susceptibility 1 candidate 1 0.064973
ANXA1 annexin A1 0.064973
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 0.064973
TMEM182 transmembrane protein 182 0.064973
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 0.064973
FAM174B family with sequence similarity 174, member B 0.064973
GLRX3 glutaredoxin 3 0.064973
BUD13 BUD13 homolog (S. cerevisiae) 0.052255
GLRX5 glutaredoxin 5 0.052255
PC pyruvate carboxylase 0.052255
PXDNL peroxidasin-like 0.052255
ZNF385D zinc finger protein 385D 0.052255
NRG3 neuregulin 3 0.052255
GPR156 G protein-coupled receptor 156 0.052255
IL32 interleukin 32 0.052255
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 0.052255
C1ORF174 chromosome 1 open reading frame 174 0.043246
AHCYL2 adenosylhomocysteinase-like 2 0.043246
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.043246
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.043246
RUNX1 runt-related transcription factor 1 0.043246
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.043246
TBC1D32 TBC1 domain family, member 32 0.043246
MAST2 microtubule associated serine/threonine kinase 2 0.043246
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.043246
PRKG2 protein kinase, cGMP-dependent, type II 0.043246
SORBS3 sorbin and SH3 domain containing 3 0.043246
CCRL2 chemokine (C-C motif) receptor-like 2 0.043246
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.035343
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 0.035343