dipivefrine-2744 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the dipivefrine-2744 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
AGFG2 ArfGAP with FG repeats 2
ALCAM activated leukocyte cell adhesion molecule
APP amyloid beta (A4) precursor protein
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B9D2 B9 protein domain 2
BCAM basal cell adhesion molecule (Lutheran blood group)
BCAN brevican
C14ORF79 chromosome 14 open reading frame 79
CAPZB capping protein (actin filament) muscle Z-line, beta
CCDC69 coiled-coil domain containing 69
CD160 CD160 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CEMIP cell migration inducing protein, hyaluronan binding
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLSTN2 calsyntenin 2
COL5A2 collagen, type V, alpha 2
COPZ2 coatomer protein complex, subunit zeta 2
DNAI2 dynein, axonemal, intermediate chain 2
EFNA3 ephrin-A3
EMID1 EMI domain containing 1
ENO3 enolase 3 (beta, muscle)
EPHB3 EPH receptor B3
ERCC6 excision repair cross-complementation group 6
FADS2 fatty acid desaturase 2
FAM214B family with sequence similarity 214, member B
FBXL7 F-box and leucine-rich repeat protein 7
FBXO11 F-box protein 11
FHL1 four and a half LIM domains 1
GHRH growth hormone releasing hormone
GPER1 G protein-coupled estrogen receptor 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAP1 huntingtin-associated protein 1
HCRP1 hepatocellular carcinoma-related HCRP1
HFE hemochromatosis
HMGN5 high mobility group nucleosome binding domain 5
HOXA1 homeobox A1
HOXB2 homeobox B2
HOXC4 homeobox C4
HSF2BP heat shock transcription factor 2 binding protein
IL1B interleukin 1, beta
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KAT6A K(lysine) acetyltransferase 6A
KAZN kazrin, periplakin interacting protein
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KHK ketohexokinase (fructokinase)
KIAA0319L KIAA0319-like
LAT2 linker for activation of T cells family, member 2
LGALS4 lectin, galactoside-binding, soluble, 4
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MED14 mediator complex subunit 14
MED27 mediator complex subunit 27
MVK mevalonate kinase
MVP major vault protein
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCR2 natural cytotoxicity triggering receptor 2
NDRG2 NDRG family member 2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
OGFR opioid growth factor receptor
OVGP1 oviductal glycoprotein 1, 120kDa
PADI3 peptidyl arginine deiminase, type III
PCDH1 protocadherin 1
PLCH1 phospholipase C, eta 1
PODNL1 podocan-like 1
POU2F2 POU class 2 homeobox 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAB33A RAB33A, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RBMS2 RNA binding motif, single stranded interacting protein 2
RRAGD Ras-related GTP binding D
SCHIP1 schwannomin interacting protein 1
SDF4 stromal cell derived factor 4
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SIGLEC6 sialic acid binding Ig-like lectin 6
SIRT5 sirtuin 5
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMOX spermine oxidase
SOX2 SRY (sex determining region Y)-box 2
TBX19 T-box 19
TDRD12 tudor domain containing 12
USB1 U6 snRNA biogenesis 1
VEGFA vascular endothelial growth factor A
WAPAL wings apart-like homolog (Drosophila)
WDR59 WD repeat domain 59
YIPF2 Yip1 domain family, member 2
ZCCHC4 zinc finger, CCHC domain containing 4
ZDHHC14 zinc finger, DHHC-type containing 14
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACSF2 acyl-CoA synthetase family member 2
AFAP1 actin filament associated protein 1
AFF4 AF4/FMR2 family, member 4
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
ANXA2P3 annexin A2 pseudogene 3
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C2ORF27A chromosome 2 open reading frame 27A
C2ORF54 chromosome 2 open reading frame 54
CBX8 chromobox homolog 8
CCNK cyclin K
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHM choroideremia (Rab escort protein 1)
CNR2 cannabinoid receptor 2 (macrophage)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAL4 dynein, axonemal, light chain 4
ELOVL4 ELOVL fatty acid elongase 4
ERN2 endoplasmic reticulum to nucleus signaling 2
EXO5 exonuclease 5
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FAM131A family with sequence similarity 131, member A
FAM189A2 family with sequence similarity 189, member A2
FAM204A family with sequence similarity 204, member A
FBXW12 F-box and WD repeat domain containing 12
FGL1 fibrinogen-like 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FZD4 frizzled class receptor 4
GINS4 GINS complex subunit 4 (Sld5 homolog)
GK3P glycerol kinase 3 pseudogene
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HMOX1 heme oxygenase 1
IL22 interleukin 22
IRF1 interferon regulatory factor 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0894 KIAA0894 protein
KLF3 Kruppel-like factor 3 (basic)
KRI1 KRI1 homolog (S. cerevisiae)
MB myoglobin
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MYO1F myosin IF
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NHEJ1 nonhomologous end-joining factor 1
NIPAL2 NIPA-like domain containing 2
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ONECUT2 one cut homeobox 2
PARD6A par-6 family cell polarity regulator alpha
PCDHA6 protocadherin alpha 6
PHACTR4 phosphatase and actin regulator 4
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRPH peripherin
RAB3A RAB3A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RIC8B RIC8 guanine nucleotide exchange factor B
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUNDC3B RUN domain containing 3B
SAYSD1 SAYSVFN motif domain containing 1
SETD8 SET domain containing (lysine methyltransferase) 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMIM14 small integral membrane protein 14
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TET3 tet methylcytosine dioxygenase 3
TICAM1 toll-like receptor adaptor molecule 1
TMEM209 transmembrane protein 209
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPST2 tyrosylprotein sulfotransferase 2
TRIM66 tripartite motif containing 66
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
USP36 ubiquitin specific peptidase 36
VEZT vezatin, adherens junctions transmembrane protein
WASF2 WAS protein family, member 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB6 zinc finger and BTB domain containing 6
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF160 zinc finger protein 160
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF408 zinc finger protein 408
ZNF480 zinc finger protein 480
ZNF552 zinc finger protein 552
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721