diphemanil metilsulfate-4591 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the diphemanil metilsulfate-4591 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ACSM3 acyl-CoA synthetase medium-chain family member 3
AFAP1 actin filament associated protein 1
AHNAK AHNAK nucleoprotein
AKAP5 A kinase (PRKA) anchor protein 5
ALDOB aldolase B, fructose-bisphosphate
ARHGAP28 Rho GTPase activating protein 28
ARNT aryl hydrocarbon receptor nuclear translocator
ATHL1 ATH1, acid trehalase-like 1 (yeast)
C10ORF10 chromosome 10 open reading frame 10
C5ORF42 chromosome 5 open reading frame 42
CAMKMT calmodulin-lysine N-methyltransferase
CCDC7 coiled-coil domain containing 7
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHN2 chimerin 2
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CIZ1 CDKN1A interacting zinc finger protein 1
CLTB clathrin, light chain B
CNGB3 cyclic nucleotide gated channel beta 3
CRTC1 CREB regulated transcription coactivator 1
CXORF21 chromosome X open reading frame 21
DOCK6 dedicator of cytokinesis 6
DUSP8 dual specificity phosphatase 8
ESRRG estrogen-related receptor gamma
ETV1 ets variant 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLJ42627 uncharacterized LOC645644
FRZB frizzled-related protein
GADD45G growth arrest and DNA-damage-inducible, gamma
GAS7 growth arrest-specific 7
GGTLC1 gamma-glutamyltransferase light chain 1
GK glycerol kinase
GPATCH2L G patch domain containing 2-like
GPATCH4 G patch domain containing 4
GRB7 growth factor receptor-bound protein 7
GTPBP10 GTP-binding protein 10 (putative)
GYPB glycophorin B (MNS blood group)
HHAT hedgehog acyltransferase
HNF1B HNF1 homeobox B
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL1RAP interleukin 1 receptor accessory protein
ITGA7 integrin, alpha 7
JAK2 Janus kinase 2
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KRIT1 KRIT1, ankyrin repeat containing
KRT31 keratin 31, type I
KYNU kynureninase
LOC157562 uncharacterized LOC157562
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK10 mitogen-activated protein kinase 10
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MPZ myelin protein zero
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYO9B myosin IXB
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCR2 natural cytotoxicity triggering receptor 2
NEK9 NIMA-related kinase 9
NEUROD1 neuronal differentiation 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NOTCH3 notch 3
NUP54 nucleoporin 54kDa
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDHGA10 protocadherin gamma subfamily A, 10
PDE5A phosphodiesterase 5A, cGMP-specific
PLBD1 phospholipase B domain containing 1
PLCG1 phospholipase C, gamma 1
RAPSN receptor-associated protein of the synapse
RGS10 regulator of G-protein signaling 10
RPP25 ribonuclease P/MRP 25kDa subunit
RPS2P45 ribosomal protein S2 pseudogene 45
SAMD4A sterile alpha motif domain containing 4A
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SNX13 sorting nexin 13
SOCS6 suppressor of cytokine signaling 6
SOGA1 suppressor of glucose, autophagy associated 1
SPON1 spondin 1, extracellular matrix protein
SPRR1A small proline-rich protein 1A
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF1 serine/arginine-rich splicing factor 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TBC1D2B TBC1 domain family, member 2B
THBS1 thrombospondin 1
TRD T cell receptor delta locus
WNK1 WNK lysine deficient protein kinase 1
XDH xanthine dehydrogenase
YTHDC2 YTH domain containing 2
YY2 YY2 transcription factor
ZBTB20 zinc finger and BTB domain containing 20
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF268 zinc finger protein 268
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ADGRB2 adhesion G protein-coupled receptor B2
ALPK1 alpha-kinase 1
ARMCX2 armadillo repeat containing, X-linked 2
ARSB arylsulfatase B
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAHCC1 BAH domain and coiled-coil containing 1
BNC1 basonuclin 1
C14ORF79 chromosome 14 open reading frame 79
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1R complement component 1, r subcomponent
C22ORF46 chromosome 22 open reading frame 46
C7ORF69 chromosome 7 open reading frame 69
CASZ1 castor zinc finger 1
CCNT1 cyclin T1
CGREF1 cell growth regulator with EF-hand domain 1
CLCA1 chloride channel accessory 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CPNE7 copine VII
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPZ carboxypeptidase Z
CRYBA2 crystallin, beta A2
CXCL3 chemokine (C-X-C motif) ligand 3
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DHDDS dehydrodolichyl diphosphate synthase
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM118A family with sequence similarity 118, member A
FBXL2 F-box and leucine-rich repeat protein 2
FBXO31 F-box protein 31
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FKBP1B FK506 binding protein 1B, 12.6 kDa
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GREB1L growth regulation by estrogen in breast cancer-like
HIST1H1T histone cluster 1, H1t
HIST1H2BM histone cluster 1, H2bm
HIST1H3C histone cluster 1, H3c
HIST1H4A histone cluster 1, H4a
IL17RB interleukin 17 receptor B
INCENP inner centromere protein antigens 135/155kDa
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LOC100287590 uncharacterized LOC100287590
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTB4R leukotriene B4 receptor
LYPD3 LY6/PLAUR domain containing 3
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MMRN2 multimerin 2
MUTYH mutY homolog
MYL5 myosin, light chain 5, regulatory
MYLIP myosin regulatory light chain interacting protein
NABP2 nucleic acid binding protein 2
NDP Norrie disease (pseudoglioma)
NOL6 nucleolar protein 6 (RNA-associated)
NUP62CL nucleoporin 62kDa C-terminal like
ODF2 outer dense fiber of sperm tails 2
PALMD palmdelphin
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PPP5C protein phosphatase 5, catalytic subunit
PRICKLE3 prickle homolog 3 (Drosophila)
PRSS53 protease, serine, 53
PTGES2 prostaglandin E synthase 2
RAB25 RAB25, member RAS oncogene family
RAB36 RAB36, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
ROM1 retinal outer segment membrane protein 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SYCP2 synaptonemal complex protein 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TCTN1 tectonic family member 1
TEX40 testis expressed 40
TMEM132A transmembrane protein 132A
TMEM209 transmembrane protein 209
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TSPAN2 tetraspanin 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VGF VGF nerve growth factor inducible
ZNF205 zinc finger protein 205
ZNF276 zinc finger protein 276
ZNF334 zinc finger protein 334
ZNF358 zinc finger protein 358
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF442 zinc finger protein 442
ZNF528 zinc finger protein 528
ZNF671 zinc finger protein 671
ZNF862 zinc finger protein 862