dioxybenzone-4638 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the dioxybenzone-4638 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADAP1 ArfGAP with dual PH domains 1
ADRA2B adrenoceptor alpha 2B
APOB apolipoprotein B
APOH apolipoprotein H (beta-2-glycoprotein I)
ARHGAP26 Rho GTPase activating protein 26
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARTN artemin
C1ORF116 chromosome 1 open reading frame 116
CCR7 chemokine (C-C motif) receptor 7
CLDN8 claudin 8
COL5A1 collagen, type V, alpha 1
CRLF1 cytokine receptor-like factor 1
CTAGE5 CTAGE family, member 5
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
EFNA3 ephrin-A3
ERC2-IT1 ERC2 intronic transcript 1
EXO5 exonuclease 5
FAM198B family with sequence similarity 198, member B
FYB FYN binding protein
GK3P glycerol kinase 3 pseudogene
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPM6B glycoprotein M6B
HDAC11 histone deacetylase 11
HEG1 heart development protein with EGF-like domains 1
HEMK1 HemK methyltransferase family member 1
HIST1H2BN histone cluster 1, H2bn
HLA-DMA major histocompatibility complex, class II, DM alpha
HLF hepatic leukemia factor
HMOX1 heme oxygenase 1
HSF1 heat shock transcription factor 1
IGF1 insulin-like growth factor 1 (somatomedin C)
INF2 inverted formin, FH2 and WH2 domain containing
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLHL22 kelch-like family member 22
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC37A3 leucine rich repeat containing 37, member A3
LYPD3 LY6/PLAUR domain containing 3
MBNL1 muscleblind-like splicing regulator 1
MLXIP MLX interacting protein
MRAS muscle RAS oncogene homolog
MYO7A myosin VIIA
NEK11 NIMA-related kinase 11
NF2 neurofibromin 2 (merlin)
NR2E3 nuclear receptor subfamily 2, group E, member 3
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAPOLB poly(A) polymerase beta (testis specific)
PARP8 poly (ADP-ribose) polymerase family, member 8
PARVA parvin, alpha
PBX2 pre-B-cell leukemia homeobox 2
PCDH1 protocadherin 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE11A phosphodiesterase 11A
PDE4D phosphodiesterase 4D, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PENK proenkephalin
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PKP1 plakophilin 1
POM121 POM121 transmembrane nucleoporin
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PRO2964 uncharacterized protein PRO2964
PRR5 proline rich 5 (renal)
RAB40C RAB40C, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
REC8 REC8 meiotic recombination protein
RIC3 RIC3 acetylcholine receptor chaperone
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS4Y1 ribosomal protein S4, Y-linked 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SELL selectin L
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SGK2 serum/glucocorticoid regulated kinase 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC25A30 solute carrier family 25, member 30
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMO smoothened, frizzled class receptor
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SPON1 spondin 1, extracellular matrix protein
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SUGP1 SURP and G patch domain containing 1
SUSD5 sushi domain containing 5
THPO thrombopoietin
UGT8 UDP glycosyltransferase 8
VAC14 Vac14 homolog (S. cerevisiae)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WT1 Wilms tumor 1
ZBTB22 zinc finger and BTB domain containing 22
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ALS2CL ALS2 C-terminal like
AMH anti-Mullerian hormone
AMT aminomethyltransferase
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BCOR BCL6 corepressor
BDNF brain-derived neurotrophic factor
BEX4 brain expressed, X-linked 4
C5ORF45 chromosome 5 open reading frame 45
CARD8 caspase recruitment domain family, member 8
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCNO cyclin O
CD72 CD72 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CHI3L2 chitinase 3-like 2
CHRDL1 chordin-like 1
CLDN1 claudin 1
CLEC10A C-type lectin domain family 10, member A
CNN1 calponin 1, basic, smooth muscle
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
DENND2D DENN/MADD domain containing 2D
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DNM3 dynamin 3
EHF ets homologous factor
EXD3 exonuclease 3'-5' domain containing 3
FBRS fibrosin
FILIP1L filamin A interacting protein 1-like
GMPR guanosine monophosphate reductase
GPATCH2L G patch domain containing 2-like
HIST1H2AG histone cluster 1, H2ag
HIST1H4E histone cluster 1, H4e
HOXA7 homeobox A7
HOXB9 homeobox B9
HPR haptoglobin-related protein
IFI6 interferon, alpha-inducible protein 6
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA1107 KIAA1107
KIAA1456 KIAA1456
KLF13 Kruppel-like factor 13
KRT20 keratin 20, type I
KRTAP1-3 keratin associated protein 1-3
LIG4 ligase IV, DNA, ATP-dependent
LINC00341 long intergenic non-protein coding RNA 341
MAP3K7CL MAP3K7 C-terminal like
MOCS3 molybdenum cofactor synthesis 3
MTG1 mitochondrial ribosome-associated GTPase 1
MTRF1 mitochondrial translational release factor 1
MTSS1L metastasis suppressor 1-like
MUC3B mucin 3B, cell surface associated
MYO1F myosin IF
NCS1 neuronal calcium sensor 1
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NEUROD1 neuronal differentiation 1
NNAT neuronatin
NR1H4 nuclear receptor subfamily 1, group H, member 4
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDE8B phosphodiesterase 8B
PER3 period circadian clock 3
PID1 phosphotyrosine interaction domain containing 1
PLAG1 pleiomorphic adenoma gene 1
PRB3 proline-rich protein BstNI subfamily 3
PRR7 proline rich 7 (synaptic)
PTPRE protein tyrosine phosphatase, receptor type, E
PTTG2 pituitary tumor-transforming 2
REPS2 RALBP1 associated Eps domain containing 2
RGCC regulator of cell cycle
RIBC2 RIB43A domain with coiled-coils 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
SAYSD1 SAYSVFN motif domain containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SECISBP2 SECIS binding protein 2
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC35F6 solute carrier family 35, member F6
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLITRK5 SLIT and NTRK-like family, member 5
SLN sarcolipin
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOX30 SRY (sex determining region Y)-box 30
SPATA2L spermatogenesis associated 2-like
STAB2 stabilin 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP4 STEAP family member 4
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TIGD6 tigger transposable element derived 6
TMEM132A transmembrane protein 132A
TMEM209 transmembrane protein 209
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSNAXIP1 translin-associated factor X interacting protein 1
VEGFB vascular endothelial growth factor B
ZNF177 zinc finger protein 177
ZNF208 zinc finger protein 208
ZNF276 zinc finger protein 276
ZNF571 zinc finger protein 571
ZNF711 zinc finger protein 711
ZNF770 zinc finger protein 770
ZXDC ZXD family zinc finger C