dihydroergocristine-7034 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dihydroergocristine-7034 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACOT11 acyl-CoA thioesterase 11
ADCK2 aarF domain containing kinase 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C10ORF95 chromosome 10 open reading frame 95
CCDC69 coiled-coil domain containing 69
CCNT2 cyclin T2
CCPG1 cell cycle progression 1
CDK16 cyclin-dependent kinase 16
CDK3 cyclin-dependent kinase 3
CEMP1 cementum protein 1
CNGB3 cyclic nucleotide gated channel beta 3
COL1A1 collagen, type I, alpha 1
COL4A1 collagen, type IV, alpha 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DOK4 docking protein 4
DYSF dysferlin
ERAP1 endoplasmic reticulum aminopeptidase 1
FBXL6 F-box and leucine-rich repeat protein 6
FGFR4 fibroblast growth factor receptor 4
FH fumarate hydratase
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD7 frizzled class receptor 7
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HIST1H2BC histone cluster 1, H2bc
HSF1 heat shock transcription factor 1
IGFALS insulin-like growth factor binding protein, acid labile subunit
INADL InaD-like (Drosophila)
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
ITPKB inositol-trisphosphate 3-kinase B
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KDM6B lysine (K)-specific demethylase 6B
KLF11 Kruppel-like factor 11
KLF13 Kruppel-like factor 13
LIG3 ligase III, DNA, ATP-dependent
LOC730101 uncharacterized LOC730101
LRRC40 leucine rich repeat containing 40
LYST lysosomal trafficking regulator
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBD1 methyl-CpG binding domain protein 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NLRX1 NLR family member X1
NRSN2 neurensin 2
OGFRL1 opioid growth factor receptor-like 1
OTUD3 OTU deubiquitinase 3
PAOX polyamine oxidase (exo-N4-amino)
PARD3 par-3 family cell polarity regulator
PARVA parvin, alpha
PCBP4 poly(rC) binding protein 4
PCDHA5 protocadherin alpha 5
PDCD6 programmed cell death 6
PDE3B phosphodiesterase 3B, cGMP-inhibited
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PKNOX1 PBX/knotted 1 homeobox 1
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAB6A RAB6A, member RAS oncogene family
RC3H2 ring finger and CCCH-type domains 2
RPL10L ribosomal protein L10-like
RSL1D1 ribosomal L1 domain containing 1
SCARB2 scavenger receptor class B, member 2
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SGSH N-sulfoglucosamine sulfohydrolase
SIDT2 SID1 transmembrane family, member 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNN stannin
SOX9 SRY (sex determining region Y)-box 9
TBCD tubulin folding cofactor D
TECTA tectorin alpha
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THOC5 THO complex 5
TMEM254 transmembrane protein 254
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIP11 thyroid hormone receptor interactor 11
TTC28 tetratricopeptide repeat domain 28
ZBTB39 zinc finger and BTB domain containing 39
ZNF3 zinc finger protein 3
ZNF324 zinc finger protein 324
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABLIM3 actin binding LIM protein family, member 3
ANXA2P3 annexin A2 pseudogene 3
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
BAHD1 bromo adjacent homology domain containing 1
C10ORF88 chromosome 10 open reading frame 88
C2ORF44 chromosome 2 open reading frame 44
C5ORF45 chromosome 5 open reading frame 45
CCDC25 coiled-coil domain containing 25
CDH10 cadherin 10, type 2 (T2-cadherin)
CHD8 chromodomain helicase DNA binding protein 8
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNN2 calponin 2
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPTP ceramide-1-phosphate transfer protein
CST6 cystatin E/M
CTSV cathepsin V
CUEDC1 CUE domain containing 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGKD diacylglycerol kinase, delta 130kDa
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
ECH1 enoyl CoA hydratase 1, peroxisomal
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL4 ELOVL fatty acid elongase 4
EPHA2 EPH receptor A2
EXD3 exonuclease 3'-5' domain containing 3
FADS3 fatty acid desaturase 3
FAM131A family with sequence similarity 131, member A
FAM193B family with sequence similarity 193, member B
FANCE Fanconi anemia, complementation group E
FOXC1 forkhead box C1
FSD1 fibronectin type III and SPRY domain containing 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR68 G protein-coupled receptor 68
GRWD1 glutamate-rich WD repeat containing 1
HIST1H2AJ histone cluster 1, H2aj
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
IL15RA interleukin 15 receptor, alpha
INCENP inner centromere protein antigens 135/155kDa
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLHL36 kelch-like family member 36
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LOC390998 ribosomal protein L10 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LYPD1 LY6/PLAUR domain containing 1
MAP1S microtubule-associated protein 1S
MCMBP minichromosome maintenance complex binding protein
MCRS1 microspherule protein 1
MFAP2 microfibrillar-associated protein 2
NECAP2 NECAP endocytosis associated 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NLK nemo-like kinase
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSTF1 osteoclast stimulating factor 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
RAB3A RAB3A, member RAS oncogene family
RECQL4 RecQ protein-like 4
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
ROM1 retinal outer segment membrane protein 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SETD8 SET domain containing (lysine methyltransferase) 8
SGK1 serum/glucocorticoid regulated kinase 1
SLC12A8 solute carrier family 12, member 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SOX12 SRY (sex determining region Y)-box 12
SSBP3 single stranded DNA binding protein 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
TDRD1 tudor domain containing 1
THBS3 thrombospondin 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM2 transmembrane protein 2
TMEM212 transmembrane protein 212
TMPRSS3 transmembrane protease, serine 3
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
TWF2 twinfilin actin binding protein 2
UBXN6 UBX domain protein 6
VWA1 von Willebrand factor A domain containing 1
WDR4 WD repeat domain 4
WDR7 WD repeat domain 7
XYLT2 xylosyltransferase II
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZMAT5 zinc finger, matrin-type 5
ZNF668 zinc finger protein 668
ZNF8 zinc finger protein 8