diflunisal-4794 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the diflunisal-4794 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
ADAM22 ADAM metallopeptidase domain 22
AGMAT agmatine ureohydrolase (agmatinase)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BEX4 brain expressed, X-linked 4
BMP4 bone morphogenetic protein 4
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTG3 BTG family, member 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF56 chromosome 1 open reading frame 56
C2ORF27A chromosome 2 open reading frame 27A
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPRIN1 cell cycle associated protein 1
CHD1L chromodomain helicase DNA binding protein 1-like
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL1A1 collagen, type I, alpha 1
COL9A3 collagen, type IX, alpha 3
CREBZF CREB/ATF bZIP transcription factor
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DUSP4 dual specificity phosphatase 4
EPHA1 EPH receptor A1
EXOC5 exocyst complex component 5
FAS Fas cell surface death receptor
FGF1 fibroblast growth factor 1 (acidic)
FGF13 fibroblast growth factor 13
FH fumarate hydratase
FOXD1 forkhead box D1
FZD1 frizzled class receptor 1
GGT1 gamma-glutamyltransferase 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
H2AFV H2A histone family, member V
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIST1H4H histone cluster 1, H4h
HOXC5 homeobox C5
ICOSLG inducible T-cell co-stimulator ligand
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KIAA0753 KIAA0753
KLHL20 kelch-like family member 20
LRRC14 leucine rich repeat containing 14
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MC3R melanocortin 3 receptor
MCAM melanoma cell adhesion molecule
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTM1 myotubularin 1
NF1 neurofibromin 1
NOL12 nucleolar protein 12
NOTCH2 notch 2
NUMA1 nuclear mitotic apparatus protein 1
NUP88 nucleoporin 88kDa
OASL 2'-5'-oligoadenylate synthetase-like
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAPPA2 pappalysin 2
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLAGL1 pleiomorphic adenoma gene-like 1
PLK3 polo-like kinase 3
PLSCR1 phospholipid scramblase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POMT2 protein-O-mannosyltransferase 2
POT1 protection of telomeres 1
PTBP3 polypyrimidine tract binding protein 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RALB v-ral simian leukemia viral oncogene homolog B
RARG retinoic acid receptor, gamma
RGS20 regulator of G-protein signaling 20
RIPK4 receptor-interacting serine-threonine kinase 4
RNF146 ring finger protein 146
SCAMP1 secretory carrier membrane protein 1
SCARB1 scavenger receptor class B, member 1
SH3BP2 SH3-domain binding protein 2
SLC35F5 solute carrier family 35, member F5
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMAD5 SMAD family member 5
SNX1 sorting nexin 1
SOD2 superoxide dismutase 2, mitochondrial
SPEG SPEG complex locus
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRSF1 serine/arginine-rich splicing factor 1
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCP11L1 t-complex 11, testis-specific-like 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
UBA6 ubiquitin-like modifier activating enzyme 6
UHRF1BP1L UHRF1 binding protein 1-like
VAV1 vav 1 guanine nucleotide exchange factor
WDTC1 WD and tetratricopeptide repeats 1
ZNF10 zinc finger protein 10
ZNF24 zinc finger protein 24
ZNF532 zinc finger protein 532
ZNF675 zinc finger protein 675

decreased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
APOC4 apolipoprotein C-IV
ATAT1 alpha tubulin acetyltransferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BFSP1 beaded filament structural protein 1, filensin
BLNK B-cell linker
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C22ORF46 chromosome 22 open reading frame 46
C9ORF9 chromosome 9 open reading frame 9
CD79B CD79b molecule, immunoglobulin-associated beta
CDK3 cyclin-dependent kinase 3
CENPO centromere protein O
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLDN9 claudin 9
CLEC16A C-type lectin domain family 16, member A
CNGB3 cyclic nucleotide gated channel beta 3
CNN2 calponin 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTSK cathepsin K
DDIT3 DNA-damage-inducible transcript 3
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DTX2 deltex 2, E3 ubiquitin ligase
EGFL7 EGF-like-domain, multiple 7
EXD3 exonuclease 3'-5' domain containing 3
EXO5 exonuclease 5
FAM46C family with sequence similarity 46, member C
FANCE Fanconi anemia, complementation group E
FBXL6 F-box and leucine-rich repeat protein 6
FBXO2 F-box protein 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPC3 glypican 3
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRB7 growth factor receptor-bound protein 7
GSTA4 glutathione S-transferase alpha 4
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HHAT hedgehog acyltransferase
HIST1H2BI histone cluster 1, H2bi
HIST1H2BJ histone cluster 1, H2bj
HIST1H4D histone cluster 1, H4d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSPA2 heat shock 70kDa protein 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL4R interleukin 4 receptor
IQCC IQ motif containing C
IQSEC2 IQ motif and Sec7 domain 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIF13A kinesin family member 13A
KRT31 keratin 31, type I
LIF leukemia inhibitory factor
LOC257152 uncharacterized LOC257152
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAP2 microtubule-associated protein 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED15 mediator complex subunit 15
MMP9 matrix metallopeptidase 9
MTERF4 mitochondrial transcription termination factor 4
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NSD1 nuclear receptor binding SET domain protein 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PCDHGA10 protocadherin gamma subfamily A, 10
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD2 phospholipase D2
PNPLA6 patatin-like phospholipase domain containing 6
PRF1 perforin 1 (pore forming protein)
PRKX protein kinase, X-linked
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RUFY2 RUN and FYVE domain containing 2
SCGB2A2 secretoglobin, family 2A, member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A8 solute carrier family 12, member 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPINK5 serine peptidase inhibitor, Kazal type 5
STEAP4 STEAP family member 4
TBC1D17 TBC1 domain family, member 17
TBC1D19 TBC1 domain family, member 19
TDRD12 tudor domain containing 12
TMEM53 transmembrane protein 53
TMEM57 transmembrane protein 57
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRIM25 tripartite motif containing 25
TSGA10 testis specific, 10
USP20 ubiquitin specific peptidase 20
VASH2 vasohibin 2
VLDLR very low density lipoprotein receptor
WDR19 WD repeat domain 19
WDR7 WD repeat domain 7
ZNF134 zinc finger protein 134
ZNF205 zinc finger protein 205
ZNF282 zinc finger protein 282
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747
ZNF767P zinc finger family member 767, pseudogene