diflorasone-2798 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the diflorasone-2798 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ALCAM activated leukocyte cell adhesion molecule
APAF1 apoptotic peptidase activating factor 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL4C ADP-ribosylation factor-like 4C
ASIC3 acid sensing (proton gated) ion channel 3
BCL6 B-cell CLL/lymphoma 6
C22ORF46 chromosome 22 open reading frame 46
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCPG1 cell cycle progression 1
CD34 CD34 molecule
CDO1 cysteine dioxygenase type 1
CGA glycoprotein hormones, alpha polypeptide
CLDN1 claudin 1
CNR2 cannabinoid receptor 2 (macrophage)
COL5A2 collagen, type V, alpha 2
CRIP1 cysteine-rich protein 1 (intestinal)
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DOCK10 dedicator of cytokinesis 10
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP9 dual specificity phosphatase 9
ELL elongation factor RNA polymerase II
FAM134A family with sequence similarity 134, member A
FBN2 fibrillin 2
FGFBP1 fibroblast growth factor binding protein 1
FMO5 flavin containing monooxygenase 5
FSCN1 fascin actin-bundling protein 1
FSCN3 fascin actin-bundling protein 3, testicular
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABARAPL1 GABA(A) receptor-associated protein like 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GLS glutaminase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GTDC1 glycosyltransferase-like domain containing 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H4A histone cluster 1, H4a
HLA-DRA major histocompatibility complex, class II, DR alpha
HSPB11 heat shock protein family B (small), member 11
ICA1 islet cell autoantigen 1, 69kDa
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
KAT6A K(lysine) acetyltransferase 6A
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIAA1107 KIAA1107
KLHL25 kelch-like family member 25
KRT17 keratin 17, type I
LAT2 linker for activation of T cells family, member 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MSL3 male-specific lethal 3 homolog (Drosophila)
MVP major vault protein
MYOZ3 myozenin 3
NDRG2 NDRG family member 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR6A1 nuclear receptor subfamily 6, group A, member 1
ONECUT2 one cut homeobox 2
OSBPL10 oxysterol binding protein-like 10
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PIGR polymeric immunoglobulin receptor
PLIN2 perilipin 2
POFUT1 protein O-fucosyltransferase 1
POPDC3 popeye domain containing 3
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PSG1 pregnancy specific beta-1-glycoprotein 1
PTRF polymerase I and transcript release factor
RASA3 RAS p21 protein activator 3
RGS4 regulator of G-protein signaling 4
RND1 Rho family GTPase 1
RNLS renalase, FAD-dependent amine oxidase
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SBF1 SET binding factor 1
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SIM2 single-minded family bHLH transcription factor 2
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
STX2 syntaxin 2
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TBX19 T-box 19
TCEAL2 transcription elongation factor A (SII)-like 2
TMEM63A transmembrane protein 63A
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRAPPC9 trafficking protein particle complex 9
UCN urocortin
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP34 ubiquitin specific peptidase 34
VAC14 Vac14 homolog (S. cerevisiae)
WSCD1 WSC domain containing 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF136 zinc finger protein 136
ZNF236 zinc finger protein 236
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ADM adrenomedullin
AUH AU RNA binding protein/enoyl-CoA hydratase
AVEN apoptosis, caspase activation inhibitor
B9D2 B9 protein domain 2
C14ORF93 chromosome 14 open reading frame 93
C1ORF159 chromosome 1 open reading frame 159
C5AR2 complement component 5a receptor 2
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC132 coiled-coil domain containing 132
CDK20 cyclin-dependent kinase 20
CEP170B centrosomal protein 170B
CHKB choline kinase beta
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNTN1 contactin 1
COPZ2 coatomer protein complex, subunit zeta 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAL4 dynein, axonemal, light chain 4
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ELOVL2 ELOVL fatty acid elongase 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FA2H fatty acid 2-hydroxylase
FAAH fatty acid amide hydrolase
FAM189A2 family with sequence similarity 189, member A2
FAM192A family with sequence similarity 192, member A
FAM204A family with sequence similarity 204, member A
FBRS fibrosin
FPGS folylpolyglutamate synthase
GFI1 growth factor independent 1 transcription repressor
GTPBP2 GTP binding protein 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H3B histone cluster 1, H3b
HOXC8 homeobox C8
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGFBP6 insulin-like growth factor binding protein 6
IGFLR1 IGF-like family receptor 1
INPP1 inositol polyphosphate-1-phosphatase
IRF7 interferon regulatory factor 7
KITLG KIT ligand
LINC00597 long intergenic non-protein coding RNA 597
LRP5 low density lipoprotein receptor-related protein 5
LYPD1 LY6/PLAUR domain containing 1
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCC mutated in colorectal cancers
MCOLN1 mucolipin 1
MTERF4 mitochondrial transcription termination factor 4
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO19 myosin XIX
MYO1E myosin IE
NAV2 neuron navigator 2
NDE1 nudE neurodevelopment protein 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NPTX1 neuronal pentraxin I
OLFML3 olfactomedin-like 3
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRSS22 protease, serine, 22
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF121 ring finger protein 121
RPGRIP1L RPGRIP1-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAYSD1 SAYSVFN motif domain containing 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOX3 SRY (sex determining region Y)-box 3
SPINK4 serine peptidase inhibitor, Kazal type 4
TGFBR3 transforming growth factor, beta receptor III
TMEM134 transmembrane protein 134
TMEM62 transmembrane protein 62
TMLHE trimethyllysine hydroxylase, epsilon
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TTC30A tetratricopeptide repeat domain 30A
TTC4 tetratricopeptide repeat domain 4
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
VIPR1 vasoactive intestinal peptide receptor 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR91 WD repeat domain 91
ZBTB22 zinc finger and BTB domain containing 22
ZBTB48 zinc finger and BTB domain containing 48
ZC3H3 zinc finger CCCH-type containing 3
ZNF571 zinc finger protein 571
ZNF639 zinc finger protein 639
ZNF701 zinc finger protein 701
ZNF862 zinc finger protein 862
ZW10 zw10 kinetochore protein