diethylcarbamazine-2394 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the diethylcarbamazine-2394 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AGRN agrin
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANK1 ankyrin 1, erythrocytic
APLP2 amyloid beta (A4) precursor-like protein 2
AQP7 aquaporin 7
ARL4C ADP-ribosylation factor-like 4C
ATF6B activating transcription factor 6 beta
BMP8A bone morphogenetic protein 8a
C19ORF66 chromosome 19 open reading frame 66
CAPN6 calpain 6
CARTPT CART prepropeptide
CRABP1 cellular retinoic acid binding protein 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF15 DDB1 and CUL4 associated factor 15
DCAF4 DDB1 and CUL4 associated factor 4
DDR1 discoidin domain receptor tyrosine kinase 1
DGCR8 DGCR8 microprocessor complex subunit
DGKG diacylglycerol kinase, gamma 90kDa
DOCK6 dedicator of cytokinesis 6
DUOX1 dual oxidase 1
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
ENO3 enolase 3 (beta, muscle)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FCAR Fc fragment of IgA receptor
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXG1 forkhead box G1
GAS8 growth arrest-specific 8
GK glycerol kinase
GLE1 GLE1 RNA export mediator
GLRA1 glycine receptor, alpha 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
HDAC7 histone deacetylase 7
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HFE hemochromatosis
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
ICA1 islet cell autoantigen 1, 69kDa
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNIP1 Kv channel interacting protein 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KYNU kynureninase
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LOXL3 lysyl oxidase-like 3
LPO lactoperoxidase
LRRC23 leucine rich repeat containing 23
LRRC75B leucine rich repeat containing 75B
LTBP3 latent transforming growth factor beta binding protein 3
MKL2 MKL/myocardin-like 2
MOG myelin oligodendrocyte glycoprotein
MXRA5 matrix-remodelling associated 5
MYO1E myosin IE
NEK1 NIMA-related kinase 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPR1 natriuretic peptide receptor 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PIGR polymeric immunoglobulin receptor
PIPOX pipecolic acid oxidase
PLCD1 phospholipase C, delta 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POU6F1 POU class 6 homeobox 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
QSER1 glutamine and serine rich 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RTEL1 regulator of telomere elongation helicase 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCN4A sodium channel, voltage gated, type IV alpha subunit
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMAD3 SMAD family member 3
SP1 Sp1 transcription factor
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SUGP1 SURP and G patch domain containing 1
THEM6 thioesterase superfamily member 6
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM63A transmembrane protein 63A
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIM23 tripartite motif containing 23
TULP3 tubby like protein 3
UBOX5 U-box domain containing 5
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
VCL vinculin
ZBTB6 zinc finger and BTB domain containing 6
ZHX3 zinc fingers and homeoboxes 3
ZNF34 zinc finger protein 34
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADTRP androgen-dependent TFPI-regulating protein
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOL6 apolipoprotein L, 6
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
ATXN2 ataxin 2
BAHCC1 BAH domain and coiled-coil containing 1
BAHD1 bromo adjacent homology domain containing 1
C16ORF59 chromosome 16 open reading frame 59
C22ORF46 chromosome 22 open reading frame 46
C2CD2 C2 calcium-dependent domain containing 2
C9ORF40 chromosome 9 open reading frame 40
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN5 calpain 5
CCDC71 coiled-coil domain containing 71
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD3EAP CD3e molecule, epsilon associated protein
CD82 CD82 molecule
CDA cytidine deaminase
CENPB centromere protein B, 80kDa
CHMP6 charged multivesicular body protein 6
CTSL cathepsin L
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CX3CR1 chemokine (C-X3-C motif) receptor 1
DCAF11 DDB1 and CUL4 associated factor 11
DDN dendrin
DKK2 dickkopf WNT signaling pathway inhibitor 2
DSCR3 Down syndrome critical region 3
ELAC1 elaC ribonuclease Z 1
ELP6 elongator acetyltransferase complex subunit 6
EML4 echinoderm microtubule associated protein like 4
FAM163A family with sequence similarity 163, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FLCN folliculin
GPR22 G protein-coupled receptor 22
GRIP2 glutamate receptor interacting protein 2
GRPR gastrin-releasing peptide receptor
GSTZ1 glutathione S-transferase zeta 1
GTF2I general transcription factor IIi
HIST2H2BE histone cluster 2, H2be
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOPX HOP homeobox
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KIAA1024 KIAA1024
LPAR4 lysophosphatidic acid receptor 4
LRP2 low density lipoprotein receptor-related protein 2
LRRC37A2 leucine rich repeat containing 37, member A2
LRRK1 leucine-rich repeat kinase 1
METTL16 methyltransferase like 16
MREG melanoregulin
MTA2 metastasis associated 1 family, member 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
MXD3 MAX dimerization protein 3
MYLIP myosin regulatory light chain interacting protein
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NIPAL2 NIPA-like domain containing 2
NPFFR1 neuropeptide FF receptor 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5DC3 5'-nucleotidase domain containing 3
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
POM121 POM121 transmembrane nucleoporin
PRKG2 protein kinase, cGMP-dependent, type II
RAB5B RAB5B, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP2 RNA polymerase II associated protein 2
RPP38 ribonuclease P/MRP 38kDa subunit
SERTAD3 SERTA domain containing 3
SIK1 salt-inducible kinase 1
SLC22A18 solute carrier family 22, member 18
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMA4 glucuronidase, beta pseudogene
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPON2 spondin 2, extracellular matrix protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM184B transmembrane protein 184B
TMEM254 transmembrane protein 254
TMOD3 tropomodulin 3 (ubiquitous)
TPK1 thiamin pyrophosphokinase 1
TRIM21 tripartite motif containing 21
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBA3C tubulin, alpha 3c
USP27X ubiquitin specific peptidase 27, X-linked
WDR60 WD repeat domain 60
ZC2HC1A zinc finger, C2HC-type containing 1A
ZNF250 zinc finger protein 250
ZNF276 zinc finger protein 276
ZNF35 zinc finger protein 35
ZNF468 zinc finger protein 468
ZNF747 zinc finger protein 747