dicoumarol-3848 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the dicoumarol-3848 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AAGAB alpha- and gamma-adaptin binding protein
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACVR1B activin A receptor, type IB
ANKFY1 ankyrin repeat and FYVE domain containing 1
BLZF1 basic leucine zipper nuclear factor 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C5AR1 complement component 5a receptor 1
CAPG capping protein (actin filament), gelsolin-like
CC2D1A coiled-coil and C2 domain containing 1A
CDC25A cell division cycle 25A
CDK14 cyclin-dependent kinase 14
COL1A1 collagen, type I, alpha 1
COL4A2 collagen, type IV, alpha 2
CTNS cystinosin, lysosomal cystine transporter
DAPK3 death-associated protein kinase 3
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DST dystonin
EHD2 EH-domain containing 2
ELAC2 elaC ribonuclease Z 2
ESR1 estrogen receptor 1
ETV4 ets variant 4
EYA3 EYA transcriptional coactivator and phosphatase 3
EZR ezrin
FADS2 fatty acid desaturase 2
FBLN1 fibulin 1
FKRP fukutin related protein
FLRT2 fibronectin leucine rich transmembrane protein 2
FUS FUS RNA binding protein
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GLIPR1 GLI pathogenesis-related 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPER1 G protein-coupled estrogen receptor 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSN gelsolin
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HFE hemochromatosis
HLF hepatic leukemia factor
HNRNPM heterogeneous nuclear ribonucleoprotein M
ICOSLG inducible T-cell co-stimulator ligand
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ING4 inhibitor of growth family, member 4
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF1C kinesin family member 1C
KLHL25 kelch-like family member 25
KMT2A lysine (K)-specific methyltransferase 2A
KRT19P2 keratin 19 pseudogene 2
LAMP1 lysosomal-associated membrane protein 1
LMAN1 lectin, mannose-binding, 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCM3AP minichromosome maintenance complex component 3 associated protein
MCOLN1 mucolipin 1
MCPH1 microcephalin 1
MED16 mediator complex subunit 16
MID1 midline 1
MON1B MON1 secretory trafficking family member B
MST1 macrophage stimulating 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCOR2 nuclear receptor corepressor 2
NFRKB nuclear factor related to kappaB binding protein
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUP50 nucleoporin 50kDa
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLK4 polo-like kinase 4
PRMT2 protein arginine methyltransferase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RB1 retinoblastoma 1
RBM5 RNA binding motif protein 5
RCAN3 RCAN family member 3
RNF126P1 ring finger protein 126 pseudogene 1
RRBP1 ribosome binding protein 1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RXRB retinoid X receptor, beta
SAFB scaffold attachment factor B
SAYSD1 SAYSVFN motif domain containing 1
SIRT4 sirtuin 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SP100 SP100 nuclear antigen
STAT4 signal transducer and activator of transcription 4
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBX5 T-box 5
TEF thyrotrophic embryonic factor
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TMCC2 transmembrane and coiled-coil domain family 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF4 TNF receptor-associated factor 4
TRIL TLR4 interactor with leucine-rich repeats
TTLL4 tubulin tyrosine ligase-like family member 4
WASL Wiskott-Aldrich syndrome-like
ZER1 zyg-11 related, cell cycle regulator
ZNF324 zinc finger protein 324

decreased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
ANKH ANKH inorganic pyrophosphate transport regulator
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD36 ankyrin repeat domain 36
ARPIN actin-related protein 2/3 complex inhibitor
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B9D2 B9 protein domain 2
BFSP1 beaded filament structural protein 1, filensin
C19ORF73 chromosome 19 open reading frame 73
C4BPA complement component 4 binding protein, alpha
CCDC9 coiled-coil domain containing 9
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CGA glycoprotein hormones, alpha polypeptide
CGREF1 cell growth regulator with EF-hand domain 1
CHRM3 cholinergic receptor, muscarinic 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCAF4 DDB1 and CUL4 associated factor 4
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAH17 dynein, axonemal, heavy chain 17
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EPHB6 EPH receptor B6
EXD3 exonuclease 3'-5' domain containing 3
FAM155A family with sequence similarity 155, member A
FAM53B family with sequence similarity 53, member B
FBXL2 F-box and leucine-rich repeat protein 2
FBXO31 F-box protein 31
FGF4 fibroblast growth factor 4
FGL1 fibrinogen-like 1
FILIP1L filamin A interacting protein 1-like
FXYD5 FXYD domain containing ion transport regulator 5
GAMT guanidinoacetate N-methyltransferase
GK3P glycerol kinase 3 pseudogene
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPR21 G protein-coupled receptor 21
GSTA4 glutathione S-transferase alpha 4
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H1B histone cluster 1, H1b
HIST1H4C histone cluster 1, H4c
HIST1H4F histone cluster 1, H4f
HOXB2 homeobox B2
IFNA14 interferon, alpha 14
JMJD4 jumonji domain containing 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF7 Kruppel-like factor 7 (ubiquitous)
LHX1 LIM homeobox 1
LIF leukemia inhibitory factor
MALL mal, T-cell differentiation protein-like
MEFV Mediterranean fever
MID1IP1 MID1 interacting protein 1
MMP3 matrix metallopeptidase 3
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NLRX1 NLR family member X1
NXPH4 neurexophilin 4
OVGP1 oviductal glycoprotein 1, 120kDa
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PMEL premelanosome protein
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PYCRL pyrroline-5-carboxylate reductase-like
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB40C RAB40C, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RELN reelin
RIN1 Ras and Rab interactor 1
RNF208 ring finger protein 208
RPL10L ribosomal protein L10-like
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPINK5 serine peptidase inhibitor, Kazal type 5
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAB2 stabilin 2
STARD8 StAR-related lipid transfer (START) domain containing 8
STIM1 stromal interaction molecule 1
TAOK1 TAO kinase 1
TBL1Y transducin (beta)-like 1, Y-linked
THRAP3 thyroid hormone receptor associated protein 3
TMEM19 transmembrane protein 19
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TONSL tonsoku-like, DNA repair protein
TOR4A torsin family 4, member A
TRIM21 tripartite motif containing 21
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VASH1 vasohibin 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF204P zinc finger protein 204, pseudogene
ZNF34 zinc finger protein 34
ZNF580 zinc finger protein 580
ZNF696 zinc finger protein 696
ZNF862 zinc finger protein 862