diclofenamide-3366 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the diclofenamide-3366 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKLE2 ankyrin repeat and LEM domain containing 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AVPR1A arginine vasopressin receptor 1A
BARX2 BARX homeobox 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BHMT betaine--homocysteine S-methyltransferase
BMP10 bone morphogenetic protein 10
C17ORF53 chromosome 17 open reading frame 53
C21ORF2 chromosome 21 open reading frame 2
CASP4 caspase 4, apoptosis-related cysteine peptidase
CC2D1A coiled-coil and C2 domain containing 1A
CCRL2 chemokine (C-C motif) receptor-like 2
CD22 CD22 molecule
CDH8 cadherin 8, type 2
CFAP45 cilia and flagella associated protein 45
CLEC4M C-type lectin domain family 4, member M
CRHR2 corticotropin releasing hormone receptor 2
CXCR6 chemokine (C-X-C motif) receptor 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCT dopachrome tautomerase
DEFA4 defensin, alpha 4, corticostatin
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DNASE1 deoxyribonuclease I
EFCAB6 EF-hand calcium binding domain 6
ELL elongation factor RNA polymerase II
ERCC2 excision repair cross-complementation group 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FABP3 fatty acid binding protein 3, muscle and heart
FGF4 fibroblast growth factor 4
FMO5 flavin containing monooxygenase 5
FSHB follicle stimulating hormone, beta polypeptide
FST follistatin
GEMIN8 gem (nuclear organelle) associated protein 8
GRIK5 glutamate receptor, ionotropic, kainate 5
GSN gelsolin
HHLA1 HERV-H LTR-associating 1
HOXD11 homeobox D11
ICOSLG inducible T-cell co-stimulator ligand
IGHD immunoglobulin heavy constant delta
IL11 interleukin 11
IL17RC interleukin 17 receptor C
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDM4B lysine (K)-specific demethylase 4B
KIAA0509 uncharacterized LOC57242
KREMEN2 kringle containing transmembrane protein 2
LGALS8 lectin, galactoside-binding, soluble, 8
LOC51145 uncharacterized LOC51145
LTC4S leukotriene C4 synthase
MDM4 MDM4, p53 regulator
MIER2 mesoderm induction early response 1, family member 2
MORN1 MORN repeat containing 1
MST1 macrophage stimulating 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYT1 myelin transcription factor 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NNAT neuronatin
NPM3 nucleophosmin/nucleoplasmin 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTF3 neurotrophin 3
NUP214 nucleoporin 214kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OMG oligodendrocyte myelin glycoprotein
PARVA parvin, alpha
PBX2 pre-B-cell leukemia homeobox 2
PDE4B phosphodiesterase 4B, cAMP-specific
PHF20L1 PHD finger protein 20-like 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PILRA paired immunoglobin-like type 2 receptor alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POU3F2 POU class 3 homeobox 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVRIG poliovirus receptor related immunoglobulin domain containing
PYY peptide YY
RAB6B RAB6B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
REEP2 receptor accessory protein 2
RGS12 regulator of G-protein signaling 12
RORC RAR-related orphan receptor C
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
SIRT5 sirtuin 5
SLC35E2 solute carrier family 35, member E2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNCAIP synuclein, alpha interacting protein
SOAT2 sterol O-acyltransferase 2
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPON1 spondin 1, extracellular matrix protein
SPTBN1 spectrin, beta, non-erythrocytic 1
STXBP6 syntaxin binding protein 6 (amisyn)
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYN3 synapsin III
TBX5 T-box 5
TBX6 T-box 6
TGM4 transglutaminase 4
TM4SF1 transmembrane 4 L six family member 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADM adrenomedullin
ATAT1 alpha tubulin acetyltransferase 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AXIN1 axin 1
BAHCC1 BAH domain and coiled-coil containing 1
BTF3P12 basic transcription factor 3 pseudogene 12
C5 complement component 5
C8ORF60 chromosome 8 open reading frame 60
CALML5 calmodulin-like 5
CCDC186 coiled-coil domain containing 186
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDK20 cyclin-dependent kinase 20
CENPO centromere protein O
CORO7 coronin 7
CORT cortistatin
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DBF4B DBF4 zinc finger B
DENND4C DENN/MADD domain containing 4C
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERCC4 excision repair cross-complementation group 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GRTP1 growth hormone regulated TBC protein 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAUS2 HAUS augmin-like complex, subunit 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HP1BP3 heterochromatin protein 1, binding protein 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT22 intraflagellar transport 22
IPP intracisternal A particle-promoted polypeptide
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
LARP6 La ribonucleoprotein domain family, member 6
LIME1 Lck interacting transmembrane adaptor 1
LOC100287590 uncharacterized LOC100287590
LOC257152 uncharacterized LOC257152
LRRC37A3 leucine rich repeat containing 37, member A3
MAGEA3 melanoma antigen family A3
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MBTD1 mbt domain containing 1
MPHOSPH8 M-phase phosphoprotein 8
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NME5 NME/NM23 family member 5
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
ONECUT2 one cut homeobox 2
PCDHGB5 protocadherin gamma subfamily B, 5
PDE12 phosphodiesterase 12
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PODNL1 podocan-like 1
POLH polymerase (DNA directed), eta
POLM polymerase (DNA directed), mu
POM121 POM121 transmembrane nucleoporin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFWD3 ring finger and WD repeat domain 3
RHOBTB2 Rho-related BTB domain containing 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SCUBE2 signal peptide, CUB domain, EGF-like 2
SECTM1 secreted and transmembrane 1
SLC16A6 solute carrier family 16, member 6
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPRYD7 SPRY domain containing 7
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TDRD1 tudor domain containing 1
TEP1 telomerase-associated protein 1
TGFBR3 transforming growth factor, beta receptor III
TIPRL TOR signaling pathway regulator
TPCN1 two pore segment channel 1
TRIM16 tripartite motif containing 16
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
VEGFC vascular endothelial growth factor C
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR76 WD repeat domain 76
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF160 zinc finger protein 160
ZNF304 zinc finger protein 304
ZNF430 zinc finger protein 430
ZNF551 zinc finger protein 551
ZNF611 zinc finger protein 611
ZNF639 zinc finger protein 639
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669
ZNF721 zinc finger protein 721