diabetes mellitus; diabetes mellitus type ii; diabetes mellitus, type 2 Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group metabolic (Genetic Association Database)
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Genes

51 genes associated with the disease diabetes mellitus; diabetes mellitus type ii; diabetes mellitus, type 2 in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACE angiotensin I converting enzyme
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ALOX5 arachidonate 5-lipoxygenase
CAPN10 calpain 10
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CREB1 cAMP responsive element binding protein 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
FOXO1 forkhead box O1
GCG glucagon
GCK glucokinase (hexokinase 4)
GCKR glucokinase (hexokinase 4) regulator
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
IL6 interleukin 6
IRS1 insulin receptor substrate 1
ITLN1 intelectin 1 (galactofuranose binding)
ITLN2 intelectin 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
LIPC lipase, hepatic
MC4R melanocortin 4 receptor
MEF2A myocyte enhancer factor 2A
MEF2D myocyte enhancer factor 2D
NEUROD1 neuronal differentiation 1
NOS3 nitric oxide synthase 3 (endothelial cell)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDX1 pancreatic and duodenal homeobox 1
PKLR pyruvate kinase, liver and RBC
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PTPN1 protein tyrosine phosphatase, non-receptor type 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
STK11 serine/threonine kinase 11
TNF tumor necrosis factor
USF1 upstream transcription factor 1