diabetes mellitus, type 2; insulin resistance Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group metabolic (Genetic Association Database)
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Genes

20 genes associated with the disease diabetes mellitus, type 2; insulin resistance in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
G6PC2 glucose-6-phosphatase, catalytic, 2
GCK glucokinase (hexokinase 4)
HHEX hematopoietically expressed homeobox
HNF1A HNF1 homeobox A
IDE insulin-degrading enzyme
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
LIPC lipase, hepatic
MCHR1 melanin-concentrating hormone receptor 1
MTNR1B melatonin receptor 1B
PPARG peroxisome proliferator-activated receptor gamma
RETN resistin
SCARB1 scavenger receptor class B, member 1
SIRT1 sirtuin 1
SLC30A8 solute carrier family 30 (zinc transporter), member 8
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)