dh domain binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket. (Gene Ontology, GO_0097161)
External Link http://amigo.geneontology.org/amigo/term/GO:0097161
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Genes

1 genes performing the dh domain binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
EPHA4 EPH receptor A4