dexpanthenol-7455 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the dexpanthenol-7455 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACRV1 acrosomal vesicle protein 1
ACTC1 actin, alpha, cardiac muscle 1
ADCY1 adenylate cyclase 1 (brain)
AIF1 allograft inflammatory factor 1
AMPD3 adenosine monophosphate deaminase 3
APOE apolipoprotein E
APOLD1 apolipoprotein L domain containing 1
AQP3 aquaporin 3 (Gill blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BICD1 bicaudal D homolog 1 (Drosophila)
BIN1 bridging integrator 1
BRS3 bombesin-like receptor 3
BTD biotinidase
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C19ORF73 chromosome 19 open reading frame 73
C22ORF31 chromosome 22 open reading frame 31
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD48 CD48 molecule
CDC25C cell division cycle 25C
CLEC4E C-type lectin domain family 4, member E
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DIO2 deiodinase, iodothyronine, type II
DLG5 discs, large homolog 5 (Drosophila)
DVL3 dishevelled segment polarity protein 3
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EHD1 EH-domain containing 1
ELOVL4 ELOVL fatty acid elongase 4
FAM65A family with sequence similarity 65, member A
FLOT1 flotillin 1
FRMD1 FERM domain containing 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GGTLC1 gamma-glutamyltransferase light chain 1
GLS glutaminase
GRTP1 growth hormone regulated TBC protein 1
GSTP1 glutathione S-transferase pi 1
HFE hemochromatosis
IFNA16 interferon, alpha 16
INO80D INO80 complex subunit D
IRS2 insulin receptor substrate 2
JAM3 junctional adhesion molecule 3
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLHL29 kelch-like family member 29
KRT13 keratin 13, type I
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRP2 low density lipoprotein receptor-related protein 2
LRP3 low density lipoprotein receptor-related protein 3
MBOAT7 membrane bound O-acyltransferase domain containing 7
MCF2L MCF.2 cell line derived transforming sequence-like
MRC2 mannose receptor, C type 2
NUP54 nucleoporin 54kDa
PADI1 peptidyl arginine deiminase, type I
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PHF20L1 PHD finger protein 20-like 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIDD1 p53-induced death domain protein 1
PLAUR plasminogen activator, urokinase receptor
PRDM2 PR domain containing 2, with ZNF domain
PRKCE protein kinase C, epsilon
PVR poliovirus receptor
RAB3D RAB3D, member RAS oncogene family
RBM5 RNA binding motif protein 5
RBP4 retinol binding protein 4, plasma
RECQL5 RecQ protein-like 5
REST RE1-silencing transcription factor
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
S100A8 S100 calcium binding protein A8
SECTM1 secreted and transmembrane 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFRP4 secreted frizzled-related protein 4
SIRT3 sirtuin 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
SYNDIG1 synapse differentiation inducing 1
SYT17 synaptotagmin XVII
TFF2 trefoil factor 2
THBS3 thrombospondin 3
THRA thyroid hormone receptor, alpha
TMC7 transmembrane channel-like 7
TMEM176A transmembrane protein 176A
TMEM2 transmembrane protein 2
TNNI3 troponin I type 3 (cardiac)
UNC5B unc-5 homolog B (C. elegans)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBED1 zinc finger, BED-type containing 1
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
AGBL5 ATP/GTP binding protein-like 5
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APH1A APH1A gamma secretase subunit
AXIN1 axin 1
BAX BCL2-associated X protein
BCCIP BRCA2 and CDKN1A interacting protein
BCL9 B-cell CLL/lymphoma 9
C16ORF45 chromosome 16 open reading frame 45
C5ORF28 chromosome 5 open reading frame 28
CA11 carbonic anhydrase XI
CCNL2 cyclin L2
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP85 centrosomal protein 85kDa
COLGALT1 collagen beta(1-O)galactosyltransferase 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTSK cathepsin K
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAL4 dynein, axonemal, light chain 4
DOCK1 dedicator of cytokinesis 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA2 EPH receptor A2
ERCC3 excision repair cross-complementation group 3
EXOC2 exocyst complex component 2
FAM53C family with sequence similarity 53, member C
FAN1 FANCD2/FANCI-associated nuclease 1
FBXL15 F-box and leucine-rich repeat protein 15
FGD6 FYVE, RhoGEF and PH domain containing 6
FGGY FGGY carbohydrate kinase domain containing
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FMO4 flavin containing monooxygenase 4
FOSL1 FOS-like antigen 1
GAB2 GRB2-associated binding protein 2
GDAP1 ganglioside induced differentiation associated protein 1
GLI3 GLI family zinc finger 3
GPR27 G protein-coupled receptor 27
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTPBP2 GTP binding protein 2
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H2AI histone cluster 1, H2ai
HMOX1 heme oxygenase 1
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JRKL JRK-like
LAMA3 laminin, alpha 3
LNPEP leucyl/cystinyl aminopeptidase
LRP5 low density lipoprotein receptor-related protein 5
LRRC61 leucine rich repeat containing 61
LYPD1 LY6/PLAUR domain containing 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MCOLN3 mucolipin 3
MECR mitochondrial trans-2-enoyl-CoA reductase
MTHFSD methenyltetrahydrofolate synthetase domain containing
MXD3 MAX dimerization protein 3
NDRG4 NDRG family member 4
NR1H3 nuclear receptor subfamily 1, group H, member 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OXTR oxytocin receptor
PARD6A par-6 family cell polarity regulator alpha
PCSK7 proprotein convertase subtilisin/kexin type 7
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G10 phospholipase A2, group X
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PTCD1 pentatricopeptide repeat domain 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RECQL4 RecQ protein-like 4
RFTN1 raftlin, lipid raft linker 1
RIPK4 receptor-interacting serine-threonine kinase 4
RNF19B ring finger protein 19B
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SAV1 salvador family WW domain containing protein 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIRT6 sirtuin 6
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC31A2 solute carrier family 31 (copper transporter), member 2
SPINK4 serine peptidase inhibitor, Kazal type 4
STK16 serine/threonine kinase 16
SUN2 Sad1 and UNC84 domain containing 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUSD4 sushi domain containing 4
TBL3 transducin (beta)-like 3
TDRD1 tudor domain containing 1
TMEM39A transmembrane protein 39A
TMEM57 transmembrane protein 57
TRAF2 TNF receptor-associated factor 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TWSG1 twisted gastrulation BMP signaling modulator 1
VASP vasodilator-stimulated phosphoprotein
ZFYVE16 zinc finger, FYVE domain containing 16
ZMAT5 zinc finger, matrin-type 5
ZNF14 zinc finger protein 14
ZNF250 zinc finger protein 250
ZNF365 zinc finger protein 365
ZNF586 zinc finger protein 586