dexamethasone-374 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dexamethasone-374 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARMC4 armadillo repeat containing 4
ARMC7 armadillo repeat containing 7
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL7C B-cell CLL/lymphoma 7C
BICD2 bicaudal D homolog 2 (Drosophila)
BTG3 BTG family, member 3
C1ORF159 chromosome 1 open reading frame 159
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CD82 CD82 molecule
CDC37L1 cell division cycle 37-like 1
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLDN15 claudin 15
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COX5B cytochrome c oxidase subunit Vb
CTC1 CTS telomere maintenance complex component 1
CUL4B cullin 4B
CXCR4 chemokine (C-X-C motif) receptor 4
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DUS2 dihydrouridine synthase 2
DXO decapping exoribonuclease
EGLN3 egl-9 family hypoxia-inducible factor 3
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELMO3 engulfment and cell motility 3
EPOR erythropoietin receptor
FSD1 fibronectin type III and SPRY domain containing 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GIMAP5 GTPase, IMAP family member 5
GLS glutaminase
GRB10 growth factor receptor-bound protein 10
GSK3A glycogen synthase kinase 3 alpha
GSTCD glutathione S-transferase, C-terminal domain containing
GTPBP2 GTP binding protein 2
H2AFY2 H2A histone family, member Y2
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IL11 interleukin 11
IL12RB1 interleukin 12 receptor, beta 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0141 KIAA0141
KLHL28 kelch-like family member 28
KLHL35 kelch-like family member 35
KREMEN2 kringle containing transmembrane protein 2
LOC100127972 uncharacterized LOC100127972
LPP LIM domain containing preferred translocation partner in lipoma
LRP3 low density lipoprotein receptor-related protein 3
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MARC1 mitochondrial amidoxime reducing component 1
MC4R melanocortin 4 receptor
MOCS2 molybdenum cofactor synthesis 2
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTFR1 mitochondrial fission regulator 1
MVP major vault protein
NXPH3 neurexophilin 3
OTUD3 OTU deubiquitinase 3
PEPD peptidase D
PEX7 peroxisomal biogenesis factor 7
PQLC3 PQ loop repeat containing 3
PRDM11 PR domain containing 11
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSIP1 PC4 and SFRS1 interacting protein 1
RANBP10 RAN binding protein 10
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS3 regulator of G-protein signaling 3
RIN2 Ras and Rab interactor 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUNX1 runt-related transcription factor 1
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SETD2 SET domain containing 2
SFXN3 sideroflexin 3
SGSH N-sulfoglucosamine sulfohydrolase
SH2B2 SH2B adaptor protein 2
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SSB Sjogren syndrome antigen B (autoantigen La)
STX7 syntaxin 7
SYT2 synaptotagmin II
SZRD1 SUZ RNA binding domain containing 1
TGM5 transglutaminase 5
THY1 Thy-1 cell surface antigen
TNK2 tyrosine kinase, non-receptor, 2
TRIO trio Rho guanine nucleotide exchange factor
UBE3A ubiquitin protein ligase E3A
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WWOX WW domain containing oxidoreductase
ZMYM4 zinc finger, MYM-type 4
ZNF460 zinc finger protein 460
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADM2 adrenomedullin 2
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARG1 arginase 1
ARR3 arrestin 3, retinal (X-arrestin)
ASIC4 acid sensing (proton gated) ion channel family member 4
AZU1 azurocidin 1
BYSL bystin-like
C16ORF59 chromosome 16 open reading frame 59
CA7 carbonic anhydrase VII
CCDC81 coiled-coil domain containing 81
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD180 CD180 molecule
CD38 CD38 molecule
CD5 CD5 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CIDEA cell death-inducing DFFA-like effector a
CLCA1 chloride channel accessory 1
CLDN14 claudin 14
CRYAB crystallin, alpha B
CSF1R colony stimulating factor 1 receptor
CSTA cystatin A (stefin A)
CXORF21 chromosome X open reading frame 21
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLK2 delta-like 2 homolog (Drosophila)
DLL3 delta-like 3 (Drosophila)
DMBT1 deleted in malignant brain tumors 1
ERC2-IT1 ERC2 intronic transcript 1
EVPL envoplakin
EXOSC9 exosome component 9
FAM106A family with sequence similarity 106, member A
FANCF Fanconi anemia, complementation group F
FBXO40 F-box protein 40
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FKTN fukutin
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAL3ST4 galactose-3-O-sulfotransferase 4
GAS8-AS1 GAS8 antisense RNA 1
GMEB1 glucocorticoid modulatory element binding protein 1
HDAC11 histone deacetylase 11
HIST1H1D histone cluster 1, H1d
HIST1H4G histone cluster 1, H4g
HMP19 HMP19 protein
HPGDS hematopoietic prostaglandin D synthase
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL15RA interleukin 15 receptor, alpha
IL19 interleukin 19
INE1 inactivation escape 1 (non-protein coding)
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LINC00574 long intergenic non-protein coding RNA 574
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEC2 melanoma antigen family C2
MAL mal, T-cell differentiation protein
MFSD11 major facilitator superfamily domain containing 11
MON1B MON1 secretory trafficking family member B
MPZ myelin protein zero
MUC2 mucin 2, oligomeric mucus/gel-forming
MXRA5 matrix-remodelling associated 5
MYBPC3 myosin binding protein C, cardiac
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYOG myogenin (myogenic factor 4)
MYOM2 myomesin 2
NCS1 neuronal calcium sensor 1
NPTX1 neuronal pentraxin I
NRAP nebulin-related anchoring protein
PENK proenkephalin
PF4 platelet factor 4
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PLA2G16 phospholipase A2, group XVI
PMEPA1 prostate transmembrane protein, androgen induced 1
POU5F1B POU class 5 homeobox 1B
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRDM1 PR domain containing 1, with ZNF domain
PROL1 proline rich, lacrimal 1
RNF141 ring finger protein 141
SCARA3 scavenger receptor class A, member 3
SCGN secretagogin, EF-hand calcium binding protein
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNORA21 small nucleolar RNA, H/ACA box 21
SPP2 secreted phosphoprotein 2, 24kDa
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAB2 stabilin 2
TINAGL1 tubulointerstitial nephritis antigen-like 1
TM7SF3 transmembrane 7 superfamily member 3
TMEM176A transmembrane protein 176A
TUBA4B tubulin, alpha 4b
UNC93B1 unc-93 homolog B1 (C. elegans)
USP29 ubiquitin specific peptidase 29
VIPR1 vasoactive intestinal peptide receptor 1
ZNF358 zinc finger protein 358
ZNF652 zinc finger protein 652
ZNHIT2 zinc finger, HIT-type containing 2