developmental Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

396 genes co-occuring with the biological term developmental in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACOT13 acyl-CoA thioesterase 13
ACTB actin, beta
ADAM10 ADAM metallopeptidase domain 10
ADAM33 ADAM metallopeptidase domain 33
ADHFE1 alcohol dehydrogenase, iron containing, 1
AFP alpha-fetoprotein
AGR2 anterior gradient 2
AGR3 anterior gradient 3
AKT3 v-akt murine thymoma viral oncogene homolog 3
AMHR2 anti-Mullerian hormone receptor, type II
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANO1 anoctamin 1, calcium activated chloride channel
ANOS1 anosmin 1
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APC adenomatous polyposis coli
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARX aristaless related homeobox
ASPN asporin
ATF2 activating transcription factor 2
B2M beta-2-microglobulin
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BDNF brain-derived neurotrophic factor
BGN biglycan
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAPN2 calpain 2, (m/II) large subunit
CAV3 caveolin 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBS cystathionine-beta-synthase
CCL13 chemokine (C-C motif) ligand 13
CCND3 cyclin D3
CD96 CD96 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKL5 cyclin-dependent kinase-like 5
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CELF2 CUGBP, Elav-like family member 2
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAT choline O-acetyltransferase
CHD7 chromodomain helicase DNA binding protein 7
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
COL1A1 collagen, type I, alpha 1
COL2A1 collagen, type II, alpha 1
COL4A1 collagen, type IV, alpha 1
COL6A4P1 collagen, type VI, alpha 4 pseudogene 1
COLEC11 collectin sub-family member 11
COMT catechol-O-methyltransferase
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRBN cereblon
CRYAB crystallin, alpha B
CRYGC crystallin, gamma C
CTAG1B cancer/testis antigen 1B
CTBP1 C-terminal binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYB5R4 cytochrome b5 reductase 4
CYLD cylindromatosis (turban tumor syndrome)
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCDC2 doublecortin domain containing 2
DEL9P Chromosome 9p deletion syndrome
DICER1 dicer 1, ribonuclease type III
DISC1 disrupted in schizophrenia 1
DLX3 distal-less homeobox 3
DLX4 distal-less homeobox 4
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DUX4L1 double homeobox 4 like 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYX1C1 dyslexia susceptibility 1 candidate 1
ECEL1 endothelin converting enzyme-like 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
ENG endoglin
ERCC1 excision repair cross-complementation group 1
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
ESR2 estrogen receptor 2 (ER beta)
EVC2 Ellis van Creveld syndrome 2
EXOSC3 exosome component 3
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2RL2 coagulation factor II (thrombin) receptor-like 2
FABP1 fatty acid binding protein 1, liver
FABP2 fatty acid binding protein 2, intestinal
FADS1 fatty acid desaturase 1
FMR1 fragile X mental retardation 1
FOXC2 forkhead box C2
FOXE3 forkhead box E3
FOXF1 forkhead box F1
FOXG1 forkhead box G1
FOXO1 forkhead box O1
FOXP1 forkhead box P1
FOXP2 forkhead box P2
FOXP3 forkhead box P3
FTO fat mass and obesity associated
FXN frataxin
FZD3 frizzled class receptor 3
G6PC3 glucose 6 phosphatase, catalytic, 3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GAGE1 G antigen 1
GDF5 growth differentiation factor 5
GDF9 growth differentiation factor 9
GHR growth hormone receptor
GJA8 gap junction protein, alpha 8, 50kDa
GJB2 gap junction protein, beta 2, 26kDa
GLI1 GLI family zinc finger 1
GLI3 GLI family zinc finger 3
GREM1 gremlin 1, DAN family BMP antagonist
GRHL3 grainyhead-like 3 (Drosophila)
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM1 glutamate receptor, metabotropic 1
GRM5 glutamate receptor, metabotropic 5
GSTP1 glutathione S-transferase pi 1
H3F3A H3 histone, family 3A
HAX1 HCLS1 associated protein X-1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HBE1 hemoglobin, epsilon 1
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HESX1 HESX homeobox 1
HIST1H1C histone cluster 1, H1c
HMGA2 high mobility group AT-hook 2
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HOXA3 homeobox A3
HOXA6 homeobox A6
HOXA9 homeobox A9
HOXA@ homeobox A cluster
HOXB9 homeobox B9
HOXD9 homeobox D9
HRAS Harvey rat sarcoma viral oncogene homolog
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSPB1 heat shock 27kDa protein 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFRD2 interferon-related developmental regulator 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL3 interleukin 3
IL6 interleukin 6
IQSEC1 IQ motif and Sec7 domain 1
IRF6 interferon regulatory factor 6
ISL1 ISL LIM homeobox 1
ITCH itchy E3 ubiquitin protein ligase
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB7 integrin, beta 7
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNK9 potassium channel, two pore domain subfamily K, member 9
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KDM1A lysine (K)-specific demethylase 1A
KDR kinase insert domain receptor
KIAA0319 KIAA0319
KLF4 Kruppel-like factor 4 (gut)
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
KRIT1 KRIT1, ankyrin repeat containing
LAMA5 laminin, alpha 5
LAMB1 laminin, beta 1
LAMC1 laminin, gamma 1 (formerly LAMB2)
LARP6 La ribonucleoprotein domain family, member 6
LCN2 lipocalin 2
LEP leptin
LEPR leptin receptor
LGALS13 lectin, galactoside-binding, soluble, 13
LHX1 LIM homeobox 1
LHX3 LIM homeobox 3
LIF leukemia inhibitory factor
LIG4 ligase IV, DNA, ATP-dependent
LIN28B lin-28 homolog B (C. elegans)
LINC00299 long intergenic non-protein coding RNA 299
LMX1A LIM homeobox transcription factor 1, alpha
LRP2 low density lipoprotein receptor-related protein 2
LZTFL1 leucine zipper transcription factor-like 1
MAGEA1 melanoma antigen family A1
MAGED1 melanoma antigen family D1
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAPT microtubule-associated protein tau
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MBD5 methyl-CpG binding domain protein 5
MBNL2 muscleblind-like splicing regulator 2
MECP2 methyl CpG binding protein 2
MEIS1 Meis homeobox 1
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MGAM maltase-glucoamylase
MIR128-1 microRNA 128-1
MIR128-2 microRNA 128-2
MIR17HG miR-17-92 cluster host gene
MIR7-1 microRNA 7-1
MIR7-2 microRNA 7-2
MIR7-3 microRNA 7-3
MRPL19 mitochondrial ribosomal protein L19
MSMO1 methylsterol monooxygenase 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH1 myosin, heavy chain 1, skeletal muscle, adult
NANOG Nanog homeobox
NANOGP8 Nanog homeobox pseudogene 8
NBN nibrin
NCAM1 neural cell adhesion molecule 1
NDN necdin, melanoma antigen (MAGE) family member
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NELFCD negative elongation factor complex member C/D
NES nestin
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NHEJ1 nonhomologous end-joining factor 1
NKAIN2 Na+/K+ transporting ATPase interacting 2
NKX2-1 NK2 homeobox 1
NKX2-2 NK2 homeobox 2
NODAL nodal growth differentiation factor
NOTCH1 notch 1
NOTCH3 notch 3
NOX1 NADPH oxidase 1
NPAS3 neuronal PAS domain protein 3
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR2E1 nuclear receptor subfamily 2, group E, member 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRP1 neuropilin 1
NRSN2 neurensin 2
NRXN1 neurexin 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTF3 neurotrophin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUMA1 nuclear mitotic apparatus protein 1
NUP98 nucleoporin 98kDa
ODAM odontogenic, ameloblast asssociated
OLFM3 olfactomedin 3
OLIG1 oligodendrocyte transcription factor 1
OLIG2 oligodendrocyte lineage transcription factor 2
OTX2 orthodenticle homeobox 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAPPA2 pappalysin 2
PARP1 poly (ADP-ribose) polymerase 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PAX6 paired box 6
PAX9 paired box 9
PDZD2 PDZ domain containing 2
PGK1 phosphoglycerate kinase 1
PHF8 PHD finger protein 8
PHOX2B paired-like homeobox 2b
PITX2 paired-like homeodomain 2
PLAC1 placenta-specific 1
PNKP polynucleotide kinase 3'-phosphatase
POC1A POC1 centriolar protein A
POC1B POC1 centriolar protein B
POLG polymerase (DNA directed), gamma
PON2 paraoxonase 2
POU4F2 POU class 4 homeobox 2
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PROP1 PROP paired-like homeobox 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRD protein tyrosine phosphatase, receptor type, D
PUM2 pumilio RNA-binding family member 2
PVR poliovirus receptor
PXDN peroxidasin
RAB39B RAB39B, member RAS oncogene family
RASL11B RAS-like, family 11, member B
RB1 retinoblastoma 1
RBL1 retinoblastoma-like 1
RBL2 retinoblastoma-like 2
RGS2 regulator of G-protein signaling 2
RGS3 regulator of G-protein signaling 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPP25 ribonuclease P/MRP 25kDa subunit
RREB1 ras responsive element binding protein 1
RUNX1 runt-related transcription factor 1
S100P S100 calcium binding protein P
SALL1 spalt-like transcription factor 1
SALL2 spalt-like transcription factor 2
SALL3 spalt-like transcription factor 3
SALL4 spalt-like transcription factor 4
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCARB1 scavenger receptor class B, member 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SCN3A sodium channel, voltage gated, type III alpha subunit
SDCBP syndecan binding protein (syntenin)
SETBP1 SET binding protein 1
SFTPA1 surfactant protein A1
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SGSH N-sulfoglucosamine sulfohydrolase
SH2B1 SH2B adaptor protein 1
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHBG sex hormone-binding globulin
SHH sonic hedgehog
SHOX short stature homeobox
SIAH1 siah E3 ubiquitin protein ligase 1
SIRT6 sirtuin 6
SIX1 SIX homeobox 1
SKOR1 SKI family transcriptional corepressor 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMOC2 SPARC related modular calcium binding 2
SNAP25 synaptosomal-associated protein, 25kDa
SOS1 son of sevenless homolog 1 (Drosophila)
SOX12 SRY (sex determining region Y)-box 12
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SOX5 SRY (sex determining region Y)-box 5
SOX9 SRY (sex determining region Y)-box 9
SP7 Sp7 transcription factor
SPI1 Spi-1 proto-oncogene
SRCAP Snf2-related CREBBP activator protein
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYT14 synaptotagmin XIV
T T, brachyury homolog (mouse)
TAC1 tachykinin, precursor 1
TBP TATA box binding protein
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDGF1 teratocarcinoma-derived growth factor 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFB1 transforming growth factor, beta 1
THRB thyroid hormone receptor, beta
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOR1B torsin family 1, member B (torsin B)
TP53 tumor protein p53
TP63 tumor protein p63
TPI1 triosephosphate isomerase 1
TSC1 tuberous sclerosis 1
TSPY1 testis specific protein, Y-linked 1
TWIST1 twist family bHLH transcription factor 1
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
UXT ubiquitously-expressed, prefoldin-like chaperone
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YY1 YY1 transcription factor
ZEB2 zinc finger E-box binding homeobox 2
ZFPM2 zinc finger protein, FOG family member 2
ZNF148 zinc finger protein 148