desoxycortone-6476 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the desoxycortone-6476 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCK2 aarF domain containing kinase 2
ADORA1 adenosine A1 receptor
AIM2 absent in melanoma 2
ANXA2P3 annexin A2 pseudogene 3
ARMCX4 armadillo repeat containing, X-linked 4
ATP10B ATPase, class V, type 10B
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BBS9 Bardet-Biedl syndrome 9
C19ORF73 chromosome 19 open reading frame 73
C2 complement component 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCKAR cholecystokinin A receptor
CDK3 cyclin-dependent kinase 3
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL8A1 collagen, type VIII, alpha 1
CORO2B coronin, actin binding protein, 2B
CSNK1G1 casein kinase 1, gamma 1
CUZD1 CUB and zona pellucida-like domains 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DUSP10 dual specificity phosphatase 10
EPAS1 endothelial PAS domain protein 1
EXT1 exostosin glycosyltransferase 1
FAM76A family with sequence similarity 76, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FGF3 fibroblast growth factor 3
FKBP10 FK506 binding protein 10, 65 kDa
FNTB farnesyltransferase, CAAX box, beta
GJA4 gap junction protein, alpha 4, 37kDa
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR1 G protein-coupled receptor 1
GRM7 glutamate receptor, metabotropic 7
GSK3A glycogen synthase kinase 3 alpha
GSPT1 G1 to S phase transition 1
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2AB histone cluster 1, H2ab
HOXB5 homeobox B5
ICA1 islet cell autoantigen 1, 69kDa
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNIP1 Kv channel interacting protein 1
LIMK1 LIM domain kinase 1
LIN7A lin-7 homolog A (C. elegans)
LPAR3 lysophosphatidic acid receptor 3
LRRC8B leucine rich repeat containing 8 family, member B
LY6G6C lymphocyte antigen 6 complex, locus G6C
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCTP2 multiple C2 domains, transmembrane 2
MECOM MDS1 and EVI1 complex locus
MEF2C myocyte enhancer factor 2C
MXRA5 matrix-remodelling associated 5
MYLK myosin light chain kinase
MYOZ3 myozenin 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NDRG2 NDRG family member 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEUROD4 neuronal differentiation 4
NRP2 neuropilin 2
ONECUT2 one cut homeobox 2
PAPPA2 pappalysin 2
PARVA parvin, alpha
PDLIM3 PDZ and LIM domain 3
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCE1 phospholipase C, epsilon 1
PLCH1 phospholipase C, eta 1
PLCL2 phospholipase C-like 2
RAB11B RAB11B, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RIN3 Ras and Rab interactor 3
RRBP1 ribosome binding protein 1
RTN2 reticulon 2
SCAPER S-phase cyclin A-associated protein in the ER
SETD8 SET domain containing (lysine methyltransferase) 8
SGCE sarcoglycan, epsilon
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNTA1 syntrophin, alpha 1
SPRED2 sprouty-related, EVH1 domain containing 2
SVIL supervillin
TACC1 transforming, acidic coiled-coil containing protein 1
TCP11L1 t-complex 11, testis-specific-like 1
TMX4 thioredoxin-related transmembrane protein 4
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRO trophinin
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TTLL4 tubulin tyrosine ligase-like family member 4
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIPF1 WAS/WASL interacting protein family, member 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF384 zinc finger protein 384

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACIN1 apoptotic chromatin condensation inducer 1
ACSF2 acyl-CoA synthetase family member 2
ADAM15 ADAM metallopeptidase domain 15
AFAP1 actin filament associated protein 1
APOLD1 apolipoprotein L domain containing 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARMCX2 armadillo repeat containing, X-linked 2
ASPN asporin
BBC3 BCL2 binding component 3
BCL2L2 BCL2-like 2
BCL7C B-cell CLL/lymphoma 7C
C5AR2 complement component 5a receptor 2
CCDC85C coiled-coil domain containing 85C
CCDC9 coiled-coil domain containing 9
CCP110 centriolar coiled coil protein 110kDa
CD79A CD79a molecule, immunoglobulin-associated alpha
CD83 CD83 molecule
CDK20 cyclin-dependent kinase 20
CEL carboxyl ester lipase
CHRM3 cholinergic receptor, muscarinic 3
CLDN17 claudin 17
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CXADR coxsackie virus and adenovirus receptor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DRD1 dopamine receptor D1
ELSPBP1 epididymal sperm binding protein 1
EN2 engrailed homeobox 2
ESRP2 epithelial splicing regulatory protein 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
FURIN furin (paired basic amino acid cleaving enzyme)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPC3 glypican 3
GPR87 G protein-coupled receptor 87
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AL histone cluster 1, H2al
HIST1H2BC histone cluster 1, H2bc
HIST1H4D histone cluster 1, H4d
HOXC4 homeobox C4
HP1BP3 heterochromatin protein 1, binding protein 3
IL12RB1 interleukin 12 receptor, beta 1
IPO8 importin 8
IRF1 interferon regulatory factor 1
LAX1 lymphocyte transmembrane adaptor 1
LGALS3 lectin, galactoside-binding, soluble, 3
LMO2 LIM domain only 2 (rhombotin-like 1)
LOXL3 lysyl oxidase-like 3
LRRC61 leucine rich repeat containing 61
LYRM9 LYR motif containing 9
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED22 mediator complex subunit 22
METTL16 methyltransferase like 16
MTERF4 mitochondrial transcription termination factor 4
MVP major vault protein
NELL2 NEL-like 2 (chicken)
NPTX1 neuronal pentraxin I
OVGP1 oviductal glycoprotein 1, 120kDa
PCDHB8 protocadherin beta 8
PHEX phosphate regulating endopeptidase homolog, X-linked
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
PRDM14 PR domain containing 14
PRMT7 protein arginine methyltransferase 7
RAPSN receptor-associated protein of the synapse
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF121 ring finger protein 121
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIDT1 SID1 transmembrane family, member 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SMA4 glucuronidase, beta pseudogene
STON1 stonin 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEAD3 TEA domain family member 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM183A transmembrane protein 183A
TMEM19 transmembrane protein 19
TMEM2 transmembrane protein 2
TMPRSS3 transmembrane protease, serine 3
TMPRSS4 transmembrane protease, serine 4
TRIM45 tripartite motif containing 45
TRIM66 tripartite motif containing 66
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
URM1 ubiquitin related modifier 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR25 WD repeat domain 25
WDR62 WD repeat domain 62
ZMAT5 zinc finger, matrin-type 5
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862