depudecin-982 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the depudecin-982 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABHD6 abhydrolase domain containing 6
ACOT8 acyl-CoA thioesterase 8
ADRBK2 adrenergic, beta, receptor kinase 2
ANKMY1 ankyrin repeat and MYND domain containing 1
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BTN2A2 butyrophilin, subfamily 2, member A2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C14ORF93 chromosome 14 open reading frame 93
C7ORF43 chromosome 7 open reading frame 43
CDC25A cell division cycle 25A
CEMIP cell migration inducing protein, hyaluronan binding
CFLAR CASP8 and FADD-like apoptosis regulator
CSRP2 cysteine and glycine-rich protein 2
CTH cystathionine gamma-lyase
DBT dihydrolipoamide branched chain transacylase E2
DESI2 desumoylating isopeptidase 2
DIXDC1 DIX domain containing 1
DMC1 DNA meiotic recombinase 1
DUSP6 dual specificity phosphatase 6
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
ESRP2 epithelial splicing regulatory protein 2
FKBP10 FK506 binding protein 10, 65 kDa
FKBP14 FK506 binding protein 14, 22 kDa
FOXO1 forkhead box O1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAMT guanidinoacetate N-methyltransferase
GLB1L galactosidase, beta 1-like
GLRX glutaredoxin (thioltransferase)
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HFE hemochromatosis
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXB7 homeobox B7
IGF1R insulin-like growth factor 1 receptor
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IRF1 interferon regulatory factor 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0895 KIAA0895
KLHL23 kelch-like family member 23
KLHL24 kelch-like family member 24
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC40 leucine rich repeat containing 40
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPT microtubule-associated protein tau
MED6 mediator complex subunit 6
MET MET proto-oncogene, receptor tyrosine kinase
MFAP3 microfibrillar-associated protein 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTM1 myotubularin 1
N4BP2L2 NEDD4 binding protein 2-like 2
NAIP NLR family, apoptosis inhibitory protein
NF2 neurofibromin 2 (merlin)
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OGFR opioid growth factor receptor
PHF14 PHD finger protein 14
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLH polymerase (DNA directed), eta
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PVR poliovirus receptor
RAB26 RAB26, member RAS oncogene family
RHOQ ras homolog family member Q
RNFT1 ring finger protein, transmembrane 1
RNFT2 ring finger protein, transmembrane 2
S100A8 S100 calcium binding protein A8
SCRN3 secernin 3
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC46A3 solute carrier family 46, member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMAD3 SMAD family member 3
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
STRN striatin, calmodulin binding protein
STYK1 serine/threonine/tyrosine kinase 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TDRKH tudor and KH domain containing
TEAD3 TEA domain family member 3
TMEM63A transmembrane protein 63A
TTC33 tetratricopeptide repeat domain 33
TXNIP thioredoxin interacting protein
UHRF1BP1L UHRF1 binding protein 1-like
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDFY3 WD repeat and FYVE domain containing 3
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF365 zinc finger protein 365
ZNF571 zinc finger protein 571
ZNF76 zinc finger protein 76
ZNF816 zinc finger protein 816

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AFF4 AF4/FMR2 family, member 4
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
BRD9 bromodomain containing 9
C11ORF30 chromosome 11 open reading frame 30
C17ORF70 chromosome 17 open reading frame 70
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC121 coiled-coil domain containing 121
CCDC94 coiled-coil domain containing 94
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHUK conserved helix-loop-helix ubiquitous kinase
CLK4 CDC-like kinase 4
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DNA2 DNA replication helicase/nuclease 2
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DUSP2 dual specificity phosphatase 2
DUSP8 dual specificity phosphatase 8
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EPM2AIP1 EPM2A (laforin) interacting protein 1
FAAH fatty acid amide hydrolase
FAM193B family with sequence similarity 193, member B
FBXL12 F-box and leucine-rich repeat protein 12
FBXL6 F-box and leucine-rich repeat protein 6
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HAUS7 HAUS augmin-like complex, subunit 7
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HIRA histone cell cycle regulator
HIST1H2AG histone cluster 1, H2ag
HIST1H3G histone cluster 1, H3g
HIST1H4C histone cluster 1, H4c
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMHA1 histocompatibility (minor) HA-1
HSPA1L heat shock 70kDa protein 1-like
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
KRT13 keratin 13, type I
LINS lines homolog (Drosophila)
LMNB1 lamin B1
LYRM9 LYR motif containing 9
METTL2B methyltransferase like 2B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
MYO19 myosin XIX
NAV2 neuron navigator 2
NDRG1 N-myc downstream regulated 1
NT5E 5'-nucleotidase, ecto (CD73)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP16 poly (ADP-ribose) polymerase family, member 16
PARPBP PARP1 binding protein
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PNPLA6 patatin-like phospholipase domain containing 6
PSKH1 protein serine kinase H1
RANBP17 RAN binding protein 17
RARS arginyl-tRNA synthetase
RPS21 ribosomal protein S21
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SEC61B Sec61 beta subunit
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SNRPF small nuclear ribonucleoprotein polypeptide F
SRSF4 serine/arginine-rich splicing factor 4
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBC1D12 TBC1 domain family, member 12
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM110 transmembrane protein 110
TMEM185B transmembrane protein 185B
TNRC6B trinucleotide repeat containing 6B
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TTLL1 tubulin tyrosine ligase-like family member 1
TUBGCP5 tubulin, gamma complex associated protein 5
ULBP2 UL16 binding protein 2
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP21 ubiquitin specific peptidase 21
VASP vasodilator-stimulated phosphoprotein
VGF VGF nerve growth factor inducible
WDR60 WD repeat domain 60
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZBTB3 zinc finger and BTB domain containing 3
ZBTB39 zinc finger and BTB domain containing 39
ZBTB40 zinc finger and BTB domain containing 40
ZNF141 zinc finger protein 141
ZNF35 zinc finger protein 35
ZNF665 zinc finger protein 665
ZNHIT2 zinc finger, HIT-type containing 2