deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-5467345
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Genes

82 proteins participating in the deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling pathway from the Reactome Pathways dataset.

Symbol Name
AES amino-terminal enhancer of split
AMER1 APC membrane recruitment protein 1
APC adenomatous polyposis coli
AXIN1 axin 1
AXIN2 axin 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CSNK1A1 casein kinase 1, alpha 1
CTBP1 C-terminal binding protein 1
CTBP2 C-terminal binding protein 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL1 cullin 1
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
LEF1 lymphoid enhancer-binding factor 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RBX1 ring-box 1, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
SKP1 S-phase kinase-associated protein 1
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE2 transducin-like enhancer of split 2
TLE3 transducin-like enhancer of split 3
TLE4 transducin-like enhancer of split 4
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C