dehydrocholic acid-4620 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the dehydrocholic acid-4620 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ADRBK1 adrenergic, beta, receptor kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
AOC3 amine oxidase, copper containing 3
ARHGAP26 Rho GTPase activating protein 26
ATF6B activating transcription factor 6 beta
BBS9 Bardet-Biedl syndrome 9
BEX1 brain expressed, X-linked 1
BLK BLK proto-oncogene, Src family tyrosine kinase
BMPR1B bone morphogenetic protein receptor, type IB
C1ORF116 chromosome 1 open reading frame 116
CADM3 cell adhesion molecule 3
CCL13 chemokine (C-C motif) ligand 13
CD4 CD4 molecule
CD58 CD58 molecule
CDK10 cyclin-dependent kinase 10
CELA2A chymotrypsin-like elastase family, member 2A
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLUAP1 clusterin associated protein 1
CNTNAP2 contactin associated protein-like 2
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTNND2 catenin (cadherin-associated protein), delta 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DGKI diacylglycerol kinase, iota
DHRS7 dehydrogenase/reductase (SDR family) member 7
DSC1 desmocollin 1
EDN3 endothelin 3
EPYC epiphycan
ERN2 endoplasmic reticulum to nucleus signaling 2
FGFR2 fibroblast growth factor receptor 2
FRK fyn-related Src family tyrosine kinase
FYB FYN binding protein
GHRHR growth hormone releasing hormone receptor
GJB3 gap junction protein, beta 3, 31kDa
GREM1 gremlin 1, DAN family BMP antagonist
GRWD1 glutamate-rich WD repeat containing 1
HEG1 heart development protein with EGF-like domains 1
HES2 hes family bHLH transcription factor 2
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPM heterogeneous nuclear ribonucleoprotein M
HRG histidine-rich glycoprotein
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
INADL InaD-like (Drosophila)
ITGA7 integrin, alpha 7
KDM6B lysine (K)-specific demethylase 6B
KRTAP9-9 keratin associated protein 9-9
LEF1 lymphoid enhancer-binding factor 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMO7 LIM domain 7
MCF2L MCF.2 cell line derived transforming sequence-like
MEG3 maternally expressed 3 (non-protein coding)
MMP11 matrix metallopeptidase 11
MRC2 mannose receptor, C type 2
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NF2 neurofibromin 2 (merlin)
NIPAL3 NIPA-like domain containing 3
PAX2 paired box 2
PDLIM3 PDZ and LIM domain 3
PDLIM5 PDZ and LIM domain 5
PGF placental growth factor
PHF20L1 PHD finger protein 20-like 1
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
POFUT1 protein O-fucosyltransferase 1
POM121 POM121 transmembrane nucleoporin
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRF1 perforin 1 (pore forming protein)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEPP1 selenoprotein P, plasma, 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SPRR2B small proline-rich protein 2B
SRD5A3 steroid 5 alpha-reductase 3
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRSF7 serine/arginine-rich splicing factor 7
SULF1 sulfatase 1
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAOK3 TAO kinase 3
TAPBP TAP binding protein (tapasin)
THEMIS2 thymocyte selection associated family member 2
TMOD1 tropomodulin 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TP63 tumor protein p63
TUBGCP2 tubulin, gamma complex associated protein 2
XYLB xylulokinase homolog (H. influenzae)
ZNF467 zinc finger protein 467
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADGRB2 adhesion G protein-coupled receptor B2
ADTRP androgen-dependent TFPI-regulating protein
AFAP1 actin filament associated protein 1
AIM2 absent in melanoma 2
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASTN1 astrotactin 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
CDH10 cadherin 10, type 2 (T2-cadherin)
CEP112 centrosomal protein 112kDa
CGA glycoprotein hormones, alpha polypeptide
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CIDEC cell death-inducing DFFA-like effector c
CRISP2 cysteine-rich secretory protein 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
DAGLA diacylglycerol lipase, alpha
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DUOX2 dual oxidase 2
DUSP10 dual specificity phosphatase 10
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM110B family with sequence similarity 110, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF6 fibroblast growth factor 6
FILIP1L filamin A interacting protein 1-like
FMO4 flavin containing monooxygenase 4
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GPC3 glypican 3
GRTP1 growth hormone regulated TBC protein 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIST1H2AL histone cluster 1, H2al
HOXB9 homeobox B9
HRH2 histamine receptor H2
HSPA1L heat shock 70kDa protein 1-like
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGKV3-20 immunoglobulin kappa variable 3-20
IL32 interleukin 32
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIAA0513 KIAA0513
KIAA1456 KIAA1456
KLF2 Kruppel-like factor 2
KRT20 keratin 20, type I
LBX1 ladybird homeobox 1
LIG4 ligase IV, DNA, ATP-dependent
LIME1 Lck interacting transmembrane adaptor 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEF1 melanoma antigen family F1
MFSD6 major facilitator superfamily domain containing 6
MMP2 matrix metallopeptidase 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL44 mitochondrial ribosomal protein L44
MTSS1L metastasis suppressor 1-like
MX1 MX dynamin-like GTPase 1
MYO1F myosin IF
NDE1 nudE neurodevelopment protein 1
NEUROD1 neuronal differentiation 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NSUN6 NOP2/Sun domain family, member 6
NTF3 neurotrophin 3
NYNRIN NYN domain and retroviral integrase containing
OLFM4 olfactomedin 4
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PDE8B phosphodiesterase 8B
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLVAP plasmalemma vesicle associated protein
PRM2 protamine 2
PRR14L proline rich 14-like
PTK7 protein tyrosine kinase 7 (inactive)
PXMP4 peroxisomal membrane protein 4, 24kDa
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RPS17P5 ribosomal protein S17 pseudogene 5
SAYSD1 SAYSVFN motif domain containing 1
SETD6 SET domain containing 6
SLC12A9 solute carrier family 12, member 9
SLN sarcolipin
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM53 transmembrane protein 53
TMPRSS4 transmembrane protease, serine 4
TOM1 target of myb1 (chicken)
ZNF208 zinc finger protein 208
ZNF606 zinc finger protein 606
ZNF747 zinc finger protein 747
ZNF813 zinc finger protein 813