dehydrocholic acid-1940 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the dehydrocholic acid-1940 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD5 abhydrolase domain containing 5
ACRV1 acrosomal vesicle protein 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGEL1 angel homolog 1 (Drosophila)
APOD apolipoprotein D
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATG10 autophagy related 10
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATXN7L3B ataxin 7-like 3B
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCL2L14 BCL2-like 14 (apoptosis facilitator)
CA7 carbonic anhydrase VII
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CLCN7 chloride channel, voltage-sensitive 7
CLTCL1 clathrin, heavy chain-like 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COPS7B COP9 signalosome subunit 7B
CRMP1 collapsin response mediator protein 1
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DENND1C DENN/MADD domain containing 1C
DLK2 delta-like 2 homolog (Drosophila)
DPF3 D4, zinc and double PHD fingers, family 3
DTNA dystrobrevin, alpha
FBLN1 fibulin 1
FMO2 flavin containing monooxygenase 2 (non-functional)
FZD8 frizzled class receptor 8
GHRHR growth hormone releasing hormone receptor
GLE1 GLE1 RNA export mediator
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPN3 GPN-loop GTPase 3
GPR1 G protein-coupled receptor 1
GPR27 G protein-coupled receptor 27
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HFE hemochromatosis
HLA-G major histocompatibility complex, class I, G
HMOX2 heme oxygenase 2
HNF1B HNF1 homeobox B
HOXD9 homeobox D9
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFT81 intraflagellar transport 81
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCTD15 potassium channel tetramerization domain containing 15
KIAA0141 KIAA0141
KLHL9 kelch-like family member 9
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LMF2 lipase maturation factor 2
MAEA macrophage erythroblast attacher
MAN1C1 mannosidase, alpha, class 1C, member 1
MEF2A myocyte enhancer factor 2A
MFGE8 milk fat globule-EGF factor 8 protein
MLH3 mutL homolog 3
MNS1 meiosis-specific nuclear structural 1
MR1 major histocompatibility complex, class I-related
MSH3 mutS homolog 3
MTG1 mitochondrial ribosome-associated GTPase 1
NELL2 NEL-like 2 (chicken)
NPTXR neuronal pentraxin receptor
NTHL1 nth endonuclease III-like 1 (E. coli)
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OSBPL2 oxysterol binding protein-like 2
PARM1 prostate androgen-regulated mucin-like protein 1
PARVA parvin, alpha
PDGFD platelet derived growth factor D
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLLP plasmolipin
POFUT1 protein O-fucosyltransferase 1
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PTAFR platelet-activating factor receptor
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RIOK3 RIO kinase 3
RNF39 ring finger protein 39
RPL23AP32 ribosomal protein L23a pseudogene 32
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S1PR1 sphingosine-1-phosphate receptor 1
SASH3 SAM and SH3 domain containing 3
SFTPB surfactant protein B
SIRT3 sirtuin 3
SKAP1 src kinase associated phosphoprotein 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLIT1 slit homolog 1 (Drosophila)
SMG7 SMG7 nonsense mediated mRNA decay factor
SNX11 sorting nexin 11
STARD3 StAR-related lipid transfer (START) domain containing 3
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBXA2R thromboxane A2 receptor
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDP1 tyrosyl-DNA phosphodiesterase 1
TMEM132A transmembrane protein 132A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
VIPR2 vasoactive intestinal peptide receptor 2
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
ZHX3 zinc fingers and homeoboxes 3
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACAD8 acyl-CoA dehydrogenase family, member 8
ACD adrenocortical dysplasia homolog (mouse)
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACVR2A activin A receptor, type IIA
AMOTL2 angiomotin like 2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APH1A APH1A gamma secretase subunit
B3GNT1
BARD1 BRCA1 associated RING domain 1
C9ORF3 chromosome 9 open reading frame 3
CDC45 cell division cycle 45
CEP85 centrosomal protein 85kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CISH cytokine inducible SH2-containing protein
CKB creatine kinase, brain
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPOX coproporphyrinogen oxidase
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DMTN dematin actin binding protein
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ERMP1 endoplasmic reticulum metallopeptidase 1
EVPL envoplakin
FADS2 fatty acid desaturase 2
FBXW12 F-box and WD repeat domain containing 12
GAMT guanidinoacetate N-methyltransferase
GCC1 GRIP and coiled-coil domain containing 1
GID4 GID complex subunit 4
H1F0 H1 histone family, member 0
HCLS1 hematopoietic cell-specific Lyn substrate 1
HEATR3 HEAT repeat containing 3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSPA4L heat shock 70kDa protein 4-like
IMPAD1 inositol monophosphatase domain containing 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
JOSD1 Josephin domain containing 1
KIF23 kinesin family member 23
KRT34 keratin 34, type I
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MAP1S microtubule-associated protein 1S
MED17 mediator complex subunit 17
MUTYH mutY homolog
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NDE1 nudE neurodevelopment protein 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOD1 nucleotide-binding oligomerization domain containing 1
NT5E 5'-nucleotidase, ecto (CD73)
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OARD1 O-acyl-ADP-ribose deacylase 1
PADI1 peptidyl arginine deiminase, type I
PCNP PEST proteolytic signal containing nuclear protein
PMM2 phosphomannomutase 2
POTEKP POTE ankyrin domain family, member K, pseudogene
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRR11 proline rich 11
PSENEN presenilin enhancer gamma secretase subunit
PTX3 pentraxin 3, long
QDPR quinoid dihydropteridine reductase
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RBBP5 retinoblastoma binding protein 5
REPIN1 replication initiator 1
RIC8A RIC8 guanine nucleotide exchange factor A
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCML1 sex comb on midleg-like 1 (Drosophila)
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SOAT1 sterol O-acyltransferase 1
SP140L SP140 nuclear body protein-like
STARD13 StAR-related lipid transfer (START) domain containing 13
STK25 serine/threonine kinase 25
STRN4 striatin, calmodulin binding protein 4
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TERF2 telomeric repeat binding factor 2
TEX30 testis expressed 30
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM115 transmembrane protein 115
TMEM164 transmembrane protein 164
TMEM260 transmembrane protein 260
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOE1 target of EGR1, member 1 (nuclear)
TOLLIP toll interacting protein
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC12 trafficking protein particle complex 12
TRHDE thyrotropin-releasing hormone degrading enzyme
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
WLS wntless Wnt ligand secretion mediator
ZFHX4 zinc finger homeobox 4
ZFP36 ZFP36 ring finger protein
ZHX2 zinc fingers and homeoboxes 2
ZNF394 zinc finger protein 394
ZNF532 zinc finger protein 532
ZNF623 zinc finger protein 623