deferoxamine-485 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the deferoxamine-485 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACAA2 acetyl-CoA acyltransferase 2
ACACA acetyl-CoA carboxylase alpha
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADIRF adipogenesis regulatory factor
ADM adrenomedullin
AIM2 absent in melanoma 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALOX5 arachidonate 5-lipoxygenase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ATG13 autophagy related 13
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BHLHE40 basic helix-loop-helix family, member e40
BIK BCL2-interacting killer (apoptosis-inducing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTN2A1 butyrophilin, subfamily 2, member A1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CADM3 cell adhesion molecule 3
CAV3 caveolin 3
CCDC85C coiled-coil domain containing 85C
CD6 CD6 molecule
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDIT4 DNA-damage-inducible transcript 4
DHRS9 dehydrogenase/reductase (SDR family) member 9
DLC1 DLC1 Rho GTPase activating protein
DLK2 delta-like 2 homolog (Drosophila)
DUSP22 dual specificity phosphatase 22
EGFL7 EGF-like-domain, multiple 7
ENO2 enolase 2 (gamma, neuronal)
FAM174B family with sequence similarity 174, member B
FGD6 FYVE, RhoGEF and PH domain containing 6
FLNC filamin C, gamma
GADD45B growth arrest and DNA-damage-inducible, beta
GAP43 growth associated protein 43
GOSR1 golgi SNAP receptor complex member 1
GYPC glycophorin C (Gerbich blood group)
HK2 hexokinase 2
KDM4B lysine (K)-specific demethylase 4B
L1CAM L1 cell adhesion molecule
LGALS8 lectin, galactoside-binding, soluble, 8
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LINC00339 long intergenic non-protein coding RNA 339
LPPR2 lipid phosphate phosphatase-related protein type 2
MBD2 methyl-CpG binding domain protein 2
MOB3B MOB kinase activator 3B
MPPED1 metallophosphoesterase domain containing 1
MYH10 myosin, heavy chain 10, non-muscle
MYL10 myosin, light chain 10, regulatory
NDRG1 N-myc downstream regulated 1
NIPAL2 NIPA-like domain containing 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
ORC4 origin recognition complex, subunit 4
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PDCD1 programmed cell death 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGK1 phosphoglycerate kinase 1
PGRMC2 progesterone receptor membrane component 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRSS53 protease, serine, 53
PSG9 pregnancy specific beta-1-glycoprotein 9
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RARA retinoic acid receptor, alpha
RING1 ring finger protein 1
RPS2 ribosomal protein S2
RUNX1 runt-related transcription factor 1
SEZ6L seizure related 6 homolog (mouse)-like
SFXN3 sideroflexin 3
SH3BP2 SH3-domain binding protein 2
SIDT2 SID1 transmembrane family, member 2
SIK3 SIK family kinase 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SOCS7 suppressor of cytokine signaling 7
SOX9 SRY (sex determining region Y)-box 9
STBD1 starch binding domain 1
SYNGR1 synaptogyrin 1
TBL2 transducin (beta)-like 2
TCF3 transcription factor 3
TCP11L1 t-complex 11, testis-specific-like 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMPRSS5 transmembrane protease, serine 5
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPMT thiopurine S-methyltransferase
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM33 tripartite motif containing 33
TWF1 twinfilin actin binding protein 1
UBOX5 U-box domain containing 5
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
ZBTB14 zinc finger and BTB domain containing 14

decreased expression

Symbol Name
AMOTL2 angiomotin like 2
ARL4A ADP-ribosylation factor-like 4A
ARSF arylsulfatase F
ATXN2 ataxin 2
AURKA aurora kinase A
AXIN1 axin 1
BCL9 B-cell CLL/lymphoma 9
BORA bora, aurora kinase A activator
C19ORF24 chromosome 19 open reading frame 24
C2 complement component 2
C7ORF43 chromosome 7 open reading frame 43
CAMKV CaM kinase-like vesicle-associated
CCL16 chemokine (C-C motif) ligand 16
CCL19 chemokine (C-C motif) ligand 19
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD5 CD5 molecule
CDC45 cell division cycle 45
CDCA8 cell division cycle associated 8
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CENPE centromere protein E, 312kDa
CKAP2 cytoskeleton associated protein 2
CLCN5 chloride channel, voltage-sensitive 5
COA7 cytochrome c oxidase assembly factor 7 (putative)
CPTP ceramide-1-phosphate transfer protein
CROT carnitine O-octanoyltransferase
CTRB2 chymotrypsinogen B2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAAM1 dishevelled associated activator of morphogenesis 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DSCAM Down syndrome cell adhesion molecule
DYSF dysferlin
EXOC6B exocyst complex component 6B
FANCF Fanconi anemia, complementation group F
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FUZ fuzzy planar cell polarity protein
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GJB1 gap junction protein, beta 1, 32kDa
GLMN glomulin, FKBP associated protein
GMEB1 glucocorticoid modulatory element binding protein 1
HIST1H1C histone cluster 1, H1c
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMMR hyaluronan-mediated motility receptor (RHAMM)
HSPB6 heat shock protein, alpha-crystallin-related, B6
IL12RB1 interleukin 12 receptor, beta 1
IRF9 interferon regulatory factor 9
JAM3 junctional adhesion molecule 3
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIF14 kinesin family member 14
KIF18B kinesin family member 18B
KIF23 kinesin family member 23
KIFC1 kinesin family member C1
KLF15 Kruppel-like factor 15
KLHL28 kelch-like family member 28
KREMEN2 kringle containing transmembrane protein 2
LENEP lens epithelial protein
LMO3 LIM domain only 3 (rhombotin-like 2)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MIP major intrinsic protein of lens fiber
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NNAT neuronatin
NOL6 nucleolar protein 6 (RNA-associated)
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPFFR1 neuropeptide FF receptor 1
NRSN2 neurensin 2
OMG oligodendrocyte myelin glycoprotein
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLK1 polo-like kinase 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRDM14 PR domain containing 14
PRODH2 proline dehydrogenase (oxidase) 2
PRR11 proline rich 11
RASL10A RAS-like, family 10, member A
RNF141 ring finger protein 141
RNF39 ring finger protein 39
STARD5 StAR-related lipid transfer (START) domain containing 5
SUSD4 sushi domain containing 4
T T, brachyury homolog (mouse)
TBCC tubulin folding cofactor C
TIMP2 TIMP metallopeptidase inhibitor 2
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TTC4 tetratricopeptide repeat domain 4
USB1 U6 snRNA biogenesis 1
VPS9D1 VPS9 domain containing 1
WDR19 WD repeat domain 19
ZBED2 zinc finger, BED-type containing 2
ZDHHC13 zinc finger, DHHC-type containing 13
ZFP36 ZFP36 ring finger protein
ZNF140 zinc finger protein 140
ZNF264 zinc finger protein 264
ZNF281 zinc finger protein 281
ZNF446 zinc finger protein 446