deferoxamine-4317 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the deferoxamine-4317 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACVR1B activin A receptor, type IB
ADGRG1 adhesion G protein-coupled receptor G1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANGPTL4 angiopoietin-like 4
ANKRD26 ankyrin repeat domain 26
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATP13A3 ATPase type 13A3
BCL2L1 BCL2-like 1
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C22ORF46 chromosome 22 open reading frame 46
CA5B carbonic anhydrase VB, mitochondrial
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD52 CD52 molecule
CD82 CD82 molecule
CFH complement factor H
CHAT choline O-acetyltransferase
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COL6A1 collagen, type VI, alpha 1
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DDIT4 DNA-damage-inducible transcript 4
DGCR14 DiGeorge syndrome critical region gene 14
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DMBT1 deleted in malignant brain tumors 1
DUSP1 dual specificity phosphatase 1
EFNA3 ephrin-A3
FABP3 fatty acid binding protein 3, muscle and heart
FBXO41 F-box protein 41
FN1 fibronectin 1
GLRA3 glycine receptor, alpha 3
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GTPBP1 GTP binding protein 1
HSF1 heat shock transcription factor 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IQSEC2 IQ motif and Sec7 domain 2
ITGB4 integrin, beta 4
JAK3 Janus kinase 3
JUND jun D proto-oncogene
KANSL3 KAT8 regulatory NSL complex subunit 3
KITLG KIT ligand
KMT2A lysine (K)-specific methyltransferase 2A
LAT2 linker for activation of T cells family, member 2
LINC00652 long intergenic non-protein coding RNA 652
LMAN1 lectin, mannose-binding, 1
LOC100294391 uncharacterized LOC100294391
LOC157562 uncharacterized LOC157562
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LTB4R leukotriene B4 receptor
MAPK7 mitogen-activated protein kinase 7
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCL1 myeloid cell leukemia 1
MED16 mediator complex subunit 16
MFN2 mitofusin 2
MOBP myelin-associated oligodendrocyte basic protein
MYH2 myosin, heavy chain 2, skeletal muscle, adult
NEBL nebulette
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NMBR neuromedin B receptor
NPTX2 neuronal pentraxin II
PAPOLG poly(A) polymerase gamma
PAWR PRKC, apoptosis, WT1, regulator
PCDH9 protocadherin 9
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIAS2 protein inhibitor of activated STAT, 2
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRKCA protein kinase C, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PXN paxillin
PYY peptide YY
RAB35 RAB35, member RAS oncogene family
RIMS3 regulating synaptic membrane exocytosis 3
RXRB retinoid X receptor, beta
SARDH sarcosine dehydrogenase
SCN1A sodium channel, voltage gated, type I alpha subunit
SIRPA signal-regulatory protein alpha
SLC17A2 solute carrier family 17, member 2
SOX21 SRY (sex determining region Y)-box 21
SOX30 SRY (sex determining region Y)-box 30
SPINK5 serine peptidase inhibitor, Kazal type 5
SPPL2B signal peptide peptidase like 2B
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRPR signal recognition particle receptor (docking protein)
TACR1 tachykinin receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNPO2 transportin 2
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
UST uronyl-2-sulfotransferase
VARS valyl-tRNA synthetase
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L2 ZFP36 ring finger protein-like 2
ZKSCAN8 zinc finger with KRAB and SCAN domains 8

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACVR2B activin A receptor, type IIB
ADGRB2 adhesion G protein-coupled receptor B2
ARL15 ADP-ribosylation factor-like 15
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BAHCC1 BAH domain and coiled-coil containing 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BEX1 brain expressed, X-linked 1
C1ORF105 chromosome 1 open reading frame 105
C1ORF54 chromosome 1 open reading frame 54
C22ORF29 chromosome 22 open reading frame 29
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD3EAP CD3e molecule, epsilon associated protein
CINP cyclin-dependent kinase 2 interacting protein
CLSPN claspin
CRY2 cryptochrome circadian clock 2
CXCL3 chemokine (C-X-C motif) ligand 3
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBF4B DBF4 zinc finger B
DCAF4 DDB1 and CUL4 associated factor 4
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
ECM1 extracellular matrix protein 1
ELOVL4 ELOVL fatty acid elongase 4
FBRS fibrosin
FBXO2 F-box protein 2
FGL1 fibrinogen-like 1
FLCN folliculin
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR3 G protein-coupled receptor 3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTPBP6 GTP binding protein 6 (putative)
HIST1H2AJ histone cluster 1, H2aj
HIST1H4C histone cluster 1, H4c
LOC257152 uncharacterized LOC257152
LRRC61 leucine rich repeat containing 61
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MED18 mediator complex subunit 18
MMRN2 multimerin 2
MTA2 metastasis associated 1 family, member 2
MYOZ3 myozenin 3
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NDP Norrie disease (pseudoglioma)
NKX3-2 NK3 homeobox 2
NME5 NME/NM23 family member 5
NOL10 nucleolar protein 10
NPDC1 neural proliferation, differentiation and control, 1
ODF2 outer dense fiber of sperm tails 2
OVGP1 oviductal glycoprotein 1, 120kDa
PAIP2B poly(A) binding protein interacting protein 2B
PARP6 poly (ADP-ribose) polymerase family, member 6
PDZK1 PDZ domain containing 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POM121L2 POM121 transmembrane nucleoporin-like 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRSS53 protease, serine, 53
PTK6 protein tyrosine kinase 6
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RFWD3 ring finger and WD repeat domain 3
RIN1 Ras and Rab interactor 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RUNX1-IT1 RUNX1 intronic transcript 1
SH2D2A SH2 domain containing 2A
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STRA6 stimulated by retinoic acid 6
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEP1 telomerase-associated protein 1
TMEM19 transmembrane protein 19
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAF2 TNF receptor-associated factor 2
TRAIP TRAF interacting protein
TRIM16 tripartite motif containing 16
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC30A tetratricopeptide repeat domain 30A
USP20 ubiquitin specific peptidase 20
VASH2 vasohibin 2
VWA1 von Willebrand factor A domain containing 1
WDR76 WD repeat domain 76
XYLT2 xylosyltransferase II
ZBTB3 zinc finger and BTB domain containing 3
ZNF219 zinc finger protein 219
ZNF264 zinc finger protein 264
ZNF446 zinc finger protein 446
ZNF552 zinc finger protein 552
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721