decreased tumor latency Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description earlier onset of tumor occurrence than expected (Mammalian Phenotype Ontology, MP_0010308)
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15 gene mutations causing the decreased tumor latency phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BRCA2 breast cancer 2, early onset
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
DCLRE1A DNA cross-link repair 1A
EGR1 early growth response 1
ERCC2 excision repair cross-complementation group 2
FOXO3 forkhead box O3
IFNG interferon, gamma
IL22RA2 interleukin 22 receptor, alpha 2
KLF10 Kruppel-like factor 10
NBN nibrin
PCSK6 proprotein convertase subtilisin/kexin type 6
PRF1 perforin 1 (pore forming protein)
RASAL2 RAS protein activator like 2
RGPD1 RANBP2-like and GRIP domain containing 1
TP53 tumor protein p53