decreased systemic arterial systolic blood pressure Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormal decrease in the pressure in the arteries as the heart contracts and pumps blood into the arteries (Mammalian Phenotype Ontology, MP_0006264)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0006264
Similar Terms
Downloads & Tools

Genes

32 gene mutations causing the decreased systemic arterial systolic blood pressure phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ACE angiotensin I converting enzyme
ACTA2 actin, alpha 2, smooth muscle, aorta
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CYBB cytochrome b-245, beta polypeptide
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DRD3 dopamine receptor D3
DUSP1 dual specificity phosphatase 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EPHX2 epoxide hydrolase 2, cytoplasmic
GHR growth hormone receptor
GLA galactosidase, alpha
GNAS GNAS complex locus
IGHMBP2 immunoglobulin mu binding protein 2
LEPR leptin receptor
NOS2 nitric oxide synthase 2, inducible
NOX1 NADPH oxidase 1
PDC phosducin
PPARA peroxisome proliferator-activated receptor alpha
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
REN renin
RGS5 regulator of G-protein signaling 5
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SPP1 secreted phosphoprotein 1
TRIB3 tribbles pseudokinase 3
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WNK4 WNK lysine deficient protein kinase 4