decreased systemic arterial blood pressure Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002843
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Genes

82 gene mutations causing the decreased systemic arterial blood pressure phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA3 adenosine A3 receptor
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARSB arylsulfatase B
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
AVPR1A arginine vasopressin receptor 1A
BSND barttin CLCNK-type chloride channel accessory beta subunit
CALCB calcitonin-related polypeptide beta
CKM creatine kinase, muscle
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLEC1B C-type lectin domain family 1, member B
CYBB cytochrome b-245, beta polypeptide
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DNM1L dynamin 1-like
DRD3 dopamine receptor D3
DUSP1 dual specificity phosphatase 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EPHX2 epoxide hydrolase 2, cytoplasmic
FGF2 fibroblast growth factor 2 (basic)
GHR growth hormone receptor
GJA5 gap junction protein, alpha 5, 40kDa
GLA galactosidase, alpha
GNAS GNAS complex locus
GPSM1 G-protein signaling modulator 1
HCRT hypocretin (orexin) neuropeptide precursor
IGHMBP2 immunoglobulin mu binding protein 2
IL10 interleukin 10
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KLF3 Kruppel-like factor 3 (basic)
LEP leptin
LEPR leptin receptor
MRVI1 murine retrovirus integration site 1 homolog
MYH11 myosin, heavy chain 11, smooth muscle
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOX1 NADPH oxidase 1
NPAS2 neuronal PAS domain protein 2
NPR1 natriuretic peptide receptor 1
NPR3 natriuretic peptide receptor 3
OXSR1 oxidative stress responsive 1
OXT oxytocin/neurophysin I prepropeptide
PCSK1 proprotein convertase subtilisin/kexin type 1
PDC phosducin
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
REN renin
RGS5 regulator of G-protein signaling 5
RORA RAR-related orphan receptor A
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SPP1 secreted phosphoprotein 1
STK39 serine threonine kinase 39
THRA thyroid hormone receptor, alpha
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRIB3 tribbles pseudokinase 3
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIM vimentin
WNK1 WNK lysine deficient protein kinase 1
WNK3 WNK lysine deficient protein kinase 3
WNK4 WNK lysine deficient protein kinase 4
WRN Werner syndrome, RecQ helicase-like
ZFP36 ZFP36 ring finger protein