decreased susceptibility to hepatic steatosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less likely than normal to develop hepatic steatosis (Mammalian Phenotype Ontology, MP_0002310)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002310
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Genes

57 gene mutations causing the decreased susceptibility to hepatic steatosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACOT11 acyl-CoA thioesterase 11
ACOT13 acyl-CoA thioesterase 13
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARRDC3 arrestin domain containing 3
C3 complement component 3
CAV1 caveolin 1, caveolae protein, 22kDa
CCAR2 cell cycle and apoptosis regulator 2
CCL13 chemokine (C-C motif) ligand 13
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CIDEC cell death-inducing DFFA-like effector c
CNOT3 CCR4-NOT transcription complex, subunit 3
COL1A1 collagen, type I, alpha 1
CRBN cereblon
CRTC3 CREB regulated transcription coactivator 3
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DUSP1 dual specificity phosphatase 1
FFAR1 free fatty acid receptor 1
G0S2 G0/G1 switch 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
JUND jun D proto-oncogene
LEP leptin
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MFSD2A major facilitator superfamily domain containing 2A
MIR378A microRNA 378a
MOGAT2 monoacylglycerol O-acyltransferase 2
MSTN myostatin
NCOA3 nuclear receptor coactivator 3
NCOR2 nuclear receptor corepressor 2
NPC1L1 NPC1-like 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
PASK PAS domain containing serine/threonine kinase
PLIN2 perilipin 2
PNRC2 proline-rich nuclear receptor coactivator 2
PPARG peroxisome proliferator-activated receptor gamma
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RCAN2 regulator of calcineurin 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERTAD2 SERTA domain containing 2
SGMS2 sphingomyelin synthase 2
SIK3 SIK family kinase 3
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SOAT2 sterol O-acyltransferase 2
SOCS2 suppressor of cytokine signaling 2
SRA1 steroid receptor RNA activator 1
SSFA2 sperm specific antigen 2
STARD10 StAR-related lipid transfer (START) domain containing 10
TICAM1 toll-like receptor adaptor molecule 1
TLR2 toll-like receptor 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UCN3 urocortin 3
UTS2 urotensin 2