decreased susceptibility to experimental autoimmune uveoretinitis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced likelihood that an organism will develop disease symptoms similar to human sight-threatening inflammatory eye diseases upon induction by peripheral immunization with one of several uveitogenic retinal proteins (or with peptides derived from them), or by the adoptive transfer of lymphocytes specific to these antigens (Mammalian Phenotype Ontology, MP_0004822)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004822
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Genes

4 gene mutations causing the decreased susceptibility to experimental autoimmune uveoretinitis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
IL1R1 interleukin 1 receptor, type I
IL27RA interleukin 27 receptor, alpha
SPP1 secreted phosphoprotein 1