decreased susceptibility to experimental autoimmune encephalomyelitis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced likelihood that an organism will develop disease symptoms similar to human multiple sclerosis upon induction with antigens to Myelin Basic Protein (MBP), Proteolipid Protein (PLP), and/or Myelin Oligodendrocyte glycoprotein (MOG) (Mammalian Phenotype Ontology, MP_0004800)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004800
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Genes

62 gene mutations causing the decreased susceptibility to experimental autoimmune encephalomyelitis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ARID5A AT rich interactive domain 5A (MRF1-like)
BATF basic leucine zipper transcription factor, ATF-like
BCL2L1 BCL2-like 1
BTK Bruton agammaglobulinemia tyrosine kinase
C3AR1 complement component 3a receptor 1
CCL13 chemokine (C-C motif) ligand 13
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR6 chemokine (C-C motif) receptor 6
CCR8 chemokine (C-C motif) receptor 8
CD28 CD28 molecule
CD44 CD44 molecule (Indian blood group)
CD5 CD5 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CIITA class II, major histocompatibility complex, transactivator
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CRH corticotropin releasing hormone
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DUSP10 dual specificity phosphatase 10
EPHB6 EPH receptor B6
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
GHRH growth hormone releasing hormone
GHRHR growth hormone releasing hormone receptor
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-E major histocompatibility complex, class I, E
HRH3 histamine receptor H3
IL13 interleukin 13
IL17A interleukin 17A
IL17C interleukin 17C
IL17F interleukin 17F
IL17RC interleukin 17 receptor C
IL21 interleukin 21
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IRAK1 interleukin-1 receptor-associated kinase 1
IRF1 interferon regulatory factor 1
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
LTA lymphotoxin alpha
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MMP9 matrix metallopeptidase 9
MOG myelin oligodendrocyte glycoprotein
MYD88 myeloid differentiation primary response 88
NINJ1 ninjurin 1
NLRP10 NLR family, pyrin domain containing 10
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PRKCQ protein kinase C, theta
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RFTN1 raftlin, lipid raft linker 1
SHCBP1 SHC SH2-domain binding protein 1
SKAP2 src kinase associated phosphoprotein 2
SPN sialophorin
STK17B serine/threonine kinase 17b
TBX21 T-box 21
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TYROBP TYRO protein tyrosine kinase binding protein