decreased susceptibility to dopaminergic neuron neurotoxicity Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than normal amount of dopaminergic neuronal cell death following exposure to a neurotoxic compound, such as MPTP-induced cell death occurring through interference in mitochondrial metabolism (Mammalian Phenotype Ontology, MP_0011452)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011452
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Genes

12 gene mutations causing the decreased susceptibility to dopaminergic neuron neurotoxicity phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
FAF1 Fas (TNFRSF6) associated factor 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
MAOB monoamine oxidase B
MAPK10 mitogen-activated protein kinase 10
PARP1 poly (ADP-ribose) polymerase 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPP1 secreted phosphoprotein 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B