decreased susceptibility to bacterial infection Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria (Mammalian Phenotype Ontology, MP_0002411)
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88 gene mutations causing the decreased susceptibility to bacterial infection phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ANTXR2 anthrax toxin receptor 2
APCS amyloid P component, serum
ARHGAP15 Rho GTPase activating protein 15
B2M beta-2-microglobulin
BAHD1 bromo adjacent homology domain containing 1
C4A complement component 4A (Rodgers blood group)
CASP12 caspase 12 (gene/pseudogene)
CBX1 chromobox homolog 1
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCR1 chemokine (C-C motif) receptor 1
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD47 CD47 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CHD7 chromodomain helicase DNA binding protein 7
CHIT1 chitinase 1 (chitotriosidase)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CORO1A coronin, actin binding protein, 1A
CSRP2BP CSRP2 binding protein
CTSG cathepsin G
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR2 chemokine (C-X-C motif) receptor 2
CYLD cylindromatosis (turban tumor syndrome)
DCN decorin
DONSON downstream neighbor of SON
EBAG9 estrogen receptor binding site associated, antigen, 9
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
ELANE elastase, neutrophil expressed
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FCMR Fc fragment of IgM receptor
FOXN1 forkhead box N1
GLT8D2 glycosyltransferase 8 domain containing 2
GUCY2C guanylate cyclase 2C
ICAM1 intercellular adhesion molecule 1
IFNB1 interferon, beta 1, fibroblast
IFNGR1 interferon gamma receptor 1
IL13 interleukin 13
IL15 interleukin 15
IL18 interleukin 18
IL1RN interleukin 1 receptor antagonist
IL27RA interleukin 27 receptor, alpha
INPP1 inositol polyphosphate-1-phosphatase
IRF5 interferon regulatory factor 5
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
MBTPS1 membrane-bound transcription factor peptidase, site 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP28 matrix metallopeptidase 28
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYO7A myosin VIIA
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
OTUD7B OTU deubiquitinase 7B
PGLYRP2 peptidoglycan recognition protein 2
PILRB paired immunoglobin-like type 2 receptor beta
PLCB2 phospholipase C, beta 2
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PRF1 perforin 1 (pore forming protein)
PTAFR platelet-activating factor receptor
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RAG2 recombination activating gene 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
S100A9 S100 calcium binding protein A9
SDC1 syndecan 1
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPP1 secreted phosphoprotein 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TERF2IP telomeric repeat binding factor 2, interacting protein
TICAM1 toll-like receptor adaptor molecule 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VTCN1 V-set domain containing T cell activation inhibitor 1
XCR1 chemokine (C motif) receptor 1