decreased spleen white pulp amount Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the quantity of the parenchymatous tissue of the spleen that surrounds splenic blood vessels, consists of compact masses of lymphatic cells and is where foreign material removed from the blood is used to initiate an immune reaction that results in the production of antibodies (Mammalian Phenotype Ontology, MP_0008479)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008479
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Genes

30 gene mutations causing the decreased spleen white pulp amount phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
AHR aryl hydrocarbon receptor
ARHGAP1 Rho GTPase activating protein 1
BCL2 B-cell CLL/lymphoma 2
DCC DCC netrin 1 receptor
DKC1 dyskeratosis congenita 1, dyskerin
GATA1 GATA binding protein 1 (globin transcription factor 1)
GON4L gon-4-like (C. elegans)
IL2RG interleukin 2 receptor, gamma
JAK2 Janus kinase 2
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LYN LYN proto-oncogene, Src family tyrosine kinase
MYB v-myb avian myeloblastosis viral oncogene homolog
NKX2-3 NK2 homeobox 3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RAG2 recombination activating gene 2
RECQL4 RecQ protein-like 4
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
STK4 serine/threonine kinase 4
T T, brachyury homolog (mouse)
TGFBR3 transforming growth factor, beta receptor III
TNF tumor necrosis factor
TTC7A tetratricopeptide repeat domain 7A
TWSG1 twisted gastrulation BMP signaling modulator 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZFPM1 zinc finger protein, FOG family member 1