decreased spleen germinal center size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced size of spleen secondary B follicles where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs (Mammalian Phenotype Ontology, MP_0008484)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008484
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Genes

20 gene mutations causing the decreased spleen germinal center size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
AHR aryl hydrocarbon receptor
BCL3 B-cell CLL/lymphoma 3
BTK Bruton agammaglobulinemia tyrosine kinase
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
CD37 CD37 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD84 CD84 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CXCL13 chemokine (C-X-C motif) ligand 13
DOCK8 dedicator of cytokinesis 8
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
MIR155 microRNA 155
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRIP10 thyroid hormone receptor interactor 10