decreased mean systemic arterial blood pressure Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description decrease in the average arterial pressure during a single cardiac cycle (Mammalian Phenotype Ontology, MP_0004876)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004876
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Genes

23 gene mutations causing the decreased mean systemic arterial blood pressure phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AGTR1 angiotensin II receptor, type 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DNM1L dynamin 1-like
FGF2 fibroblast growth factor 2 (basic)
GJA5 gap junction protein, alpha 5, 40kDa
GPSM1 G-protein signaling modulator 1
HCRT hypocretin (orexin) neuropeptide precursor
IL10 interleukin 10
KLF3 Kruppel-like factor 3 (basic)
MYH11 myosin, heavy chain 11, smooth muscle
NOS1 nitric oxide synthase 1 (neuronal)
NPAS2 neuronal PAS domain protein 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
REN renin
RGS5 regulator of G-protein signaling 5
RORA RAR-related orphan receptor A
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
STK39 serine threonine kinase 39
THRA thyroid hormone receptor, alpha
VIM vimentin