decreased interleukin-9 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the production or release of a multifunctional cytokine secreted by primarily by activated TH2 cells that may play a role as a regulator of allergic inflammation, and has been shown to enhance the growth and differentiation of mast cells, and can act on a variety of other immune cells (Mammalian Phenotype Ontology, MP_0008712)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008712
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Genes

6 gene mutations causing the decreased interleukin-9 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
IL13 interleukin 13
IL17RA interleukin 17 receptor A
IL17RB interleukin 17 receptor B
IL23R interleukin 23 receptor
IL25 interleukin 25
NFIL3 nuclear factor, interleukin 3 regulated