decreased interleukin-23 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the production or release of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells (Mammalian Phenotype Ontology, MP_0008691)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008691
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Genes

5 gene mutations causing the decreased interleukin-23 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CARD9 caspase recruitment domain family, member 9
CLEC6A C-type lectin domain family 6, member A
FASTK Fas-activated serine/threonine kinase
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
MUC5B mucin 5B, oligomeric mucus/gel-forming