decreased interleukin-1 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the production or release of a soluble factor produced by monocytes, macrophages and other cells, which activates T-lymphocytes and potentiates their response to mitogens or antigens (Mammalian Phenotype Ontology, MP_0008652)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008652
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Genes

2 gene mutations causing the decreased interleukin-1 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
TLR2 toll-like receptor 2