decreased dn4 thymocyte number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of thymocytes that have the cell surface marker phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive. (Mammalian Phenotype Ontology, MP_0010136)
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5 gene mutations causing the decreased dn4 thymocyte number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CDK6 cyclin-dependent kinase 6
DCLRE1C DNA cross-link repair 1C
PRKCH protein kinase C, eta
PTCRA pre T-cell antigen receptor alpha
ZBTB1 zinc finger and BTB domain containing 1